Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   NWE22_RS08115 Genome accession   NZ_CP102747
Coordinates   1576815..1579061 (+) Length   748 a.a.
NCBI ID   WP_277745374.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SFJ45     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1571815..1584061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE22_RS08090 (NWE22_08090) - 1572752..1573660 (+) 909 WP_171989204.1 neutral zinc metallopeptidase -
  NWE22_RS08095 (NWE22_08095) - 1573741..1574592 (-) 852 WP_130554559.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  NWE22_RS08100 (NWE22_08100) - 1574721..1575455 (-) 735 WP_174845581.1 amino acid ABC transporter ATP-binding protein -
  NWE22_RS08105 (NWE22_08105) - 1575463..1576137 (-) 675 WP_171989206.1 amino acid ABC transporter permease -
  NWE22_RS08110 (NWE22_08110) - 1576256..1576486 (-) 231 WP_024392448.1 DUF1797 family protein -
  NWE22_RS08115 (NWE22_08115) clpE 1576815..1579061 (+) 2247 WP_277745374.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  NWE22_RS08120 (NWE22_08120) - 1579208..1579675 (+) 468 WP_174845583.1 NUDIX hydrolase -
  NWE22_RS08125 (NWE22_08125) - 1579722..1580030 (+) 309 WP_024396912.1 DUF1827 family protein -
  NWE22_RS08130 (NWE22_08130) ileS 1580093..1582882 (-) 2790 WP_274505950.1 isoleucine--tRNA ligase -
  NWE22_RS08135 (NWE22_08135) - 1582893..1583336 (-) 444 WP_171989210.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 748 a.a.        Molecular weight: 83360.82 Da        Isoelectric Point: 5.2853

>NTDB_id=718704 NWE22_RS08115 WP_277745374.1 1576815..1579061(+) (clpE) [Streptococcus parasuis strain SFJ45]
MLCTNCKINDATIHLYTNMNGKQQKVDLCHNCYQIMKTDPNNAILRGLGENLTNPNNMDPFSEFFNHLGGYPGNTPAGKN
RDQTPPTQAGGGNGGGRFNQPNAGQTQTVPQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLI
GEPGVGKTAVVEGLAQKIVDGDVPHKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREVILFIDEIHEIVGA
GSAGDGNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQNKYQDYHHVKYS
PEAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIDAENRKEQATRDEDYEKAAYYRDQIAKY
KEMQKATISEEDIPLITEKEIEAIIEQKTNIPVGELKEKEQSQLIHLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGAPN
RPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLIL
LDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLGNFFTPEFM
NRFDGIIEFQPLTKENLLQIVSLMLEDVNRRLSTNGIRLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYL
ENPNEKDLRAVMTNKGTIQIKAQPPKEK

Nucleotide


Download         Length: 2247 bp        

>NTDB_id=718704 NWE22_RS08115 WP_277745374.1 1576815..1579061(+) (clpE) [Streptococcus parasuis strain SFJ45]
ATGCTCTGTACAAACTGTAAAATAAATGATGCTACCATTCATCTCTATACAAATATGAATGGCAAACAACAGAAAGTTGA
CCTTTGCCATAATTGTTATCAAATTATGAAAACGGATCCAAATAATGCTATCTTACGTGGCTTAGGGGAGAACTTAACTA
ATCCAAACAATATGGATCCCTTTAGTGAATTTTTCAATCATTTAGGTGGTTACCCTGGTAATACCCCAGCTGGTAAGAAT
CGAGATCAAACACCTCCTACTCAAGCAGGCGGTGGCAACGGTGGTGGTCGATTCAATCAACCAAATGCGGGTCAAACCCA
AACAGTCCCACAACCAAATGGATTGCTGGAAGAATTTGGGATTAATGTTACTGAGATTGCACGACGTGGAGATATTGACC
CCGTTATCGGACGCGATCAAGAAATCACTCGGGTGATTGAAATTTTGAACCGTCGCACCAAAAACAACCCCGTTCTTATC
GGTGAGCCCGGTGTTGGTAAAACTGCAGTCGTTGAAGGACTAGCACAAAAAATTGTAGACGGGGACGTTCCACATAAACT
TCAAAACAAAGAAGTCATTCGATTAGACGTTGTCAGCCTTGTTCAAGGAACAGGAATCCGAGGTCAATTTGAAGAACGCA
TGCAAAAACTCATGGAAGAAATTCGGAACCGACGTGAAGTTATTCTCTTCATTGATGAAATTCATGAGATTGTCGGAGCT
GGTTCTGCAGGAGATGGAAACATGGATGCCGGCAATATTCTAAAACCCGCCCTCGCTCGTGGTGAAATGCAACTGGTCGG
TGCTACTACTTTAAATGAATACCGCATTATTGAAAAAGATGCAGCTCTTGAACGTCGGATGCAACCTGTAAAAGTTGACG
AACCAAGTGTTGAAGAAACAATCACTATCTTAAAAGGTATTCAGAATAAATACCAAGACTACCACCATGTAAAATATTCC
CCTGAGGCAATTGAAGCTGCGGCCGTATTATCCAACCGCTATATTCAAGACCGATTCTTACCTGATAAAGCGATTGATTT
GCTAGACGAAGCTGGATCAAAAATGAACTTAACCTTGAACTTCGTAGATCCTAAAGAAATTGACCAACGGTTAATTGATG
CCGAAAATCGTAAAGAACAAGCAACTCGTGATGAAGATTACGAAAAAGCTGCCTATTATCGTGACCAAATTGCTAAATAT
AAAGAAATGCAAAAGGCAACGATTAGTGAGGAGGATATTCCTCTCATTACCGAAAAAGAAATCGAAGCCATCATTGAACA
AAAAACAAATATCCCTGTTGGCGAGCTGAAAGAAAAAGAACAGTCTCAATTGATACATTTGGCAAGTGATCTCAAAGCGC
ATGTCATTGGACAAGACGATGCTGTTGATAAAATTGCAAAAGCAATCCGTCGCAATCGTGTAGGACTTGGAGCACCAAAT
CGTCCAATTGGTTCCTTCTTATTCGTAGGACCTACTGGCGTCGGTAAAACAGAATTATCAAAACAATTAGCCATTGAGCT
CTTCGGTTCAGCGGACAGCATGATTCGATTTGATATGTCTGAATATATGGAAAAACACGCAGTTGCAAAACTAGTCGGTG
CCCCTCCTGGATATGTGGGGTATGAAGAAGCTGGCCAACTAACAGAAAAAGTCCGTCGCAATCCATACTCACTCATTCTC
CTTGATGAAGTTGAAAAGGCGCATCCAGATGTGATGCACATGTTCCTACAAGTTCTTGATGACGGTCGACTGACAGATGG
ACAAGGGCGAACAGTCAGCTTCAAAGATACCATTATCATTATGACTTCAAATGCTGGTACAGGTAAGGTTGAGGCCAGCG
TGGGATTTGGAGCCGCTATGGAAGGTCGTACACAATCTGTTCTTGGCCAACTCGGTAATTTCTTCACTCCCGAATTCATG
AACCGCTTCGATGGAATTATTGAATTCCAACCACTTACAAAAGAAAATCTGCTCCAAATTGTCAGTCTCATGCTGGAAGA
CGTCAACCGTCGCTTATCTACAAACGGTATTCGACTACATGTGACCGATAAAGTAAAGGAAAAATTAGTTGATCTTGGTT
ACGATCCTAAAATGGGTGCACGTCCCCTTCGCAGGACCATTCAAGACCAAATTGAAGATGCCATTACCGATTTCTATTTA
GAGAATCCTAATGAGAAAGATTTACGAGCTGTCATGACCAATAAAGGCACCATCCAAATCAAAGCTCAACCGCCAAAAGA
AAAATAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(158-277)

AAA lid domain (AAA_lid_9)

(296-394)

AAA domain (Cdc48 subfamily) (AAA_2)

(481-644)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(652-724)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.713

100

0.832
  clpE Streptococcus pneumoniae D39

82.713

100

0.832
  clpE Streptococcus pneumoniae R6

82.713

100

0.832
  clpE Streptococcus pneumoniae TIGR4

82.713

100

0.832
  clpE Streptococcus mutans UA159

83.087

99.599

0.828
  clpC Lactococcus lactis subsp. cremoris KW2

76.438

97.594

0.746
  clpC Bacillus subtilis subsp. subtilis str. 168

51.008

86.23

0.44
  clpC Streptococcus mutans UA159

47.91

83.155

0.398
  clpC Streptococcus pneumoniae Rx1

47.444

83.69

0.397
  clpC Streptococcus pneumoniae D39

47.444

83.69

0.397
  clpC Streptococcus pneumoniae TIGR4

47.444

83.69

0.397
  clpC Streptococcus thermophilus LMD-9

47.125

83.69

0.394
  clpC Streptococcus thermophilus LMG 18311

46.805

83.69

0.392
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.85

82.754

0.388