Detailed information    

insolico Bioinformatically predicted

Overview

Name   radA   Type   Machinery gene
Locus tag   NWE22_RS00725 Genome accession   NZ_CP102747
Coordinates   139315..140682 (+) Length   455 a.a.
NCBI ID   WP_130554220.1    Uniprot ID   A0A4Q8L3V7
Organism   Streptococcus parasuis strain SFJ45     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 138774..158129 139315..140682 within 0


Gene organization within MGE regions


Location: 138774..158129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE22_RS00720 (NWE22_00720) - 138774..139308 (+) 535 Protein_121 histidine phosphatase family protein -
  NWE22_RS00725 (NWE22_00725) radA 139315..140682 (+) 1368 WP_130554220.1 DNA repair protein RadA Machinery gene
  NWE22_RS00730 (NWE22_00730) - 140806..141300 (+) 495 WP_171988974.1 carbonic anhydrase -
  NWE22_RS00735 (NWE22_00735) - 141500..142258 (+) 759 WP_171988973.1 TIGR00266 family protein -
  NWE22_RS00740 (NWE22_00740) - 142431..142556 (+) 126 WP_274505519.1 hypothetical protein -
  NWE22_RS00745 (NWE22_00745) - 142543..142914 (+) 372 WP_239604448.1 hypothetical protein -
  NWE22_RS00750 (NWE22_00750) gltX 143303..144757 (+) 1455 WP_239604449.1 glutamate--tRNA ligase -
  NWE22_RS00755 (NWE22_00755) - 144798..145310 (-) 513 WP_239604450.1 adenylate kinase -
  NWE22_RS00760 (NWE22_00760) - 145307..145672 (-) 366 WP_174846595.1 MerR family transcriptional regulator -
  NWE22_RS00765 (NWE22_00765) - 145733..146023 (+) 291 WP_239604451.1 hypothetical protein -
  NWE22_RS00770 (NWE22_00770) - 146020..146511 (-) 492 WP_239604452.1 NUDIX hydrolase -
  NWE22_RS10310 - 146633..147508 (+) 876 Protein_132 VOC family protein -
  NWE22_RS00790 (NWE22_00790) - 147612..148139 (+) 528 WP_024397302.1 transcription repressor NadR -
  NWE22_RS00795 (NWE22_00795) - 148210..148758 (+) 549 WP_171988969.1 hypothetical protein -
  NWE22_RS00800 (NWE22_00800) - 148950..150143 (+) 1194 WP_171988968.1 argininosuccinate synthase -
  NWE22_RS00805 (NWE22_00805) argH 150157..151551 (+) 1395 WP_171988967.1 argininosuccinate lyase -
  NWE22_RS00810 (NWE22_00810) rnpA 151622..151981 (+) 360 WP_174846592.1 ribonuclease P protein component -
  NWE22_RS00815 (NWE22_00815) - 151965..152777 (+) 813 WP_174846591.1 YidC/Oxa1 family membrane protein insertase -
  NWE22_RS00820 (NWE22_00820) jag 152796..153800 (+) 1005 WP_239604455.1 RNA-binding cell elongation regulator Jag/EloR -
  NWE22_RS00825 (NWE22_00825) rpmH 154022..154159 (+) 138 WP_049618373.1 50S ribosomal protein L34 -
  NWE22_RS00830 (NWE22_00830) - 154209..155090 (-) 882 WP_174846590.1 diacylglycerol kinase family protein -
  NWE22_RS00835 (NWE22_00835) - 155240..156022 (+) 783 WP_171988962.1 TatD family hydrolase -
  NWE22_RS00840 (NWE22_00840) rnmV 156006..156572 (+) 567 WP_171989046.1 ribonuclease M5 -
  NWE22_RS00845 (NWE22_00845) - 156565..156693 (+) 129 WP_275577031.1 hypothetical protein -
  NWE22_RS00850 (NWE22_00850) - 156789..156959 (+) 171 WP_239604456.1 hypothetical protein -
  NWE22_RS00855 (NWE22_00855) - 156966..157218 (+) 253 Protein_146 NUDIX domain-containing protein -
  NWE22_RS00860 (NWE22_00860) rsmA 157257..158129 (+) 873 WP_171988961.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 49884.38 Da        Isoelectric Point: 6.1911

>NTDB_id=718678 NWE22_RS00725 WP_130554220.1 139315..140682(+) (radA) [Streptococcus parasuis strain SFJ45]
MIIAKKKTTFVCQNCEYHSPKYLGRCPNCGSWSSFVEEVEVAEVKNERVSLTGEKTRPMKLNEVSSIQVARTKTNMEEFN
RVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSTIGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSIRTE
IEKIKPDFLIIDSIQTIMSPDISSVQGSVSQVREVTNELMQIAKTNNIATFIVGHMTKEGTLAGPRTLEHMVDTVLYFEG
ERQHTFRILRAVKNRFGSTNEIGIFEMQSQGLVEVLNPSEVFLEERLDGATGSAIVVTMEGTRPILAEVQALVTPSMFGN
AKRTTTGLDFNRASLIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVALASSYKDKPTNPQECFIGEIGLTGE
IRRVNRIEQRINEAAKLGFTKVYAPKNSLTGIKVPKEITVIGVTTIGEVLQKVFN

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=718678 NWE22_RS00725 WP_130554220.1 139315..140682(+) (radA) [Streptococcus parasuis strain SFJ45]
ATCATCATCGCTAAGAAAAAAACAACCTTTGTCTGCCAAAATTGTGAATACCATTCGCCCAAGTATCTGGGCCGTTGCCC
CAACTGTGGCTCCTGGTCTAGCTTTGTCGAGGAAGTTGAAGTCGCTGAAGTCAAGAACGAGCGGGTTAGCCTGACAGGTG
AGAAGACCCGTCCAATGAAACTCAATGAAGTTTCCTCCATTCAAGTGGCTCGCACCAAGACCAACATGGAGGAGTTTAAC
CGTGTCCTCGGTGGCGGTGTGGTGCCAGGGAGTCTGGTCCTGATCGGAGGCGATCCAGGGATTGGCAAATCCACCCTACT
CTTGCAAGTTTCAACACAGCTTTCGACCATTGGTACCGTCCTCTATGTGTCCGGGGAAGAGTCTGCCCAGCAGATTAAGT
TGCGGGCGGAACGTTTGGGCGACATCGACAGCGAGTTCTATCTCTATGCGGAGACCAATATGCAGAGCATTCGGACCGAG
ATTGAAAAGATTAAGCCAGATTTCCTGATTATCGACTCTATCCAGACCATTATGAGTCCTGACATTTCTAGCGTACAAGG
TTCTGTCAGTCAGGTCCGTGAAGTGACCAATGAACTCATGCAAATTGCTAAGACCAACAACATTGCAACCTTTATCGTCG
GTCACATGACCAAGGAAGGAACCCTGGCTGGACCGCGGACCTTGGAGCATATGGTAGACACCGTTCTTTATTTTGAAGGC
GAGCGGCAGCATACCTTTCGTATCTTGCGGGCGGTCAAAAACCGCTTTGGCTCCACCAACGAAATCGGCATTTTTGAAAT
GCAGTCACAGGGTTTGGTCGAAGTCCTCAATCCTAGTGAGGTCTTTCTGGAAGAGCGTTTGGACGGGGCGACAGGCTCTG
CTATTGTCGTGACCATGGAGGGCACCCGCCCTATCCTTGCGGAAGTGCAGGCTCTGGTGACCCCGAGCATGTTTGGCAAT
GCCAAGCGGACCACGACAGGCTTGGACTTCAACCGTGCCAGCTTGATTATGGCGGTTTTGGAAAAACGGGCAGGCCTGCT
CCTCCAAAACCAAGATGCCTACCTTAAGTCAGCTGGCGGTGTCAAACTGGATGAGCCAGCTATTGACCTGGCGGTCGCAG
TTGCCCTTGCCTCCAGTTACAAAGATAAGCCAACCAACCCACAAGAGTGCTTTATAGGCGAGATTGGCCTGACAGGTGAA
ATCCGCCGTGTCAATCGGATTGAGCAACGGATTAACGAAGCCGCTAAATTGGGCTTTACCAAGGTCTATGCTCCTAAAAA
TTCTCTGACCGGTATCAAGGTGCCCAAGGAAATAACGGTTATCGGCGTGACAACAATTGGCGAAGTTCTGCAAAAAGTGT
TTAACTAA

Domains

Predicted by InterproScan.

AAA domain (AAA_25)

(64-220)

Subunit ChlI of Mg-chelatase (ChlI)

(363-427)

Rubredoxin metal binding domain (Zn_ribbon_LapB)

(10-37)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Q8L3V7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  radA Streptococcus mitis NCTC 12261

91.372

99.341

0.908
  radA Streptococcus pneumoniae Rx1

91.15

99.341

0.905
  radA Streptococcus pneumoniae D39

91.15

99.341

0.905
  radA Streptococcus pneumoniae R6

91.15

99.341

0.905
  radA Streptococcus pneumoniae TIGR4

91.15

99.341

0.905
  radA Streptococcus mitis SK321

90.929

99.341

0.903
  radA Bacillus subtilis subsp. subtilis str. 168

62.252

99.56

0.62