Detailed information NTG0717600

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: NUU05_RS00355
• Genome accession: NZ_CP102538
• Coordinates: 61713..64163 (-)
• Length: 816 a.a.
• NCBI ID: WP_011680614.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TH-4
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 56713..69163

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NUU05_RS00340 (NUU05_00335)	pbp3	57249..58496 (+)	1248	WP_014621034.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
NUU05_RS00350 (NUU05_00345)	pbp3	60353..61585 (+)	1233	Protein_51	D-alanyl-D-alanine carboxypeptidase PBP3	-
NUU05_RS00355 (NUU05_00350)	clpC	61713..64163 (-)	2451	WP_011680614.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NUU05_RS00360 (NUU05_00355)	-	64164..64619 (-)	456	WP_002949111.1	CtsR family transcriptional regulator	-
NUU05_RS00365 (NUU05_00360)	-	64863..65333 (+)	471	WP_011680613.1	small multi-drug export protein	-
NUU05_RS00370 (NUU05_00365)	tsf	65443..66483 (-)	1041	WP_002949105.1	translation elongation factor Ts	-
NUU05_RS00375 (NUU05_00370)	rpsB	66601..67368 (-)	768	WP_011680612.1	30S ribosomal protein S2	-
NUU05_RS00385 (NUU05_00380)	-	67891..68846 (+)	956	Protein_57	S66 peptidase family protein	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90404.55 Da
• Isoelectric Point: 5.6107

>NTDB_id=717600 NUU05_RS00355 WP_011680614.1 61713..64163(-) (clpC) [Streptococcus thermophilus strain TH-4]
MTIYSRKMQAIFHRAQLEAERFESPFLETWHVLLAMVEVTGSVAYLTFTDFEDRIHSEEIETAAVLAMEKRPKDLSESDI
IDLRAQSPALEAMLQEAQEIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERNAGLS
KQDLKAIHDLRKPKKSKASANFANMMQPPQSSTGELADYTKDLTALAESGNLDPVIGRDEEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVSEAIDILNGLRSSYEDYHRVTI
TDAAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQVRIKKEDKREITPLDEALISGDIGAAVKQYKANQKAKFPKPAL
VDADQIMQTLSRLSGIPVEKMTQTDSKRYLNLESELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEIEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQTISHNHQAMQARIMEELKKSYRPEFINRIDEKVV
FHSLEEEQLHDIVKIMVKPLISALADKGISLKFQPAALKHLAKDGYDIEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=717600 NUU05_RS00355 WP_011680614.1 61713..64163(-) (clpC) [Streptococcus thermophilus strain TH-4]
ATGACGATATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAAGCGGAGCGTTTTGAAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTAACGGGATCTGTAGCCTACTTAACATTTACTGATTTTGAGGACC
GTATTCATTCGGAAGAGATTGAGACAGCTGCTGTATTGGCTATGGAGAAGAGGCCAAAAGACTTATCGGAATCAGATATT
ATCGATTTACGTGCACAGTCACCTGCGCTAGAGGCTATGTTGCAAGAGGCGCAAGAAATCGCTAGTGTTACTGGTGCTGT
AGAGGTGGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTAATGGTTTGTCGCCTCCTTGAAGTGGCTG
GTTTTCAATATAAAGATGATAGCGATAAACCTCGCATCATAGATTTACGACGTTCTTTGGAGCGTAATGCTGGTCTTAGC
AAGCAAGATTTGAAGGCAATTCACGATCTTCGTAAACCTAAGAAATCAAAAGCATCTGCGAATTTTGCCAATATGATGCA
ACCTCCTCAATCATCTACTGGTGAACTGGCAGATTATACCAAAGACTTAACTGCATTAGCGGAGTCAGGAAATCTTGATC
CCGTTATTGGACGCGATGAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAATCCTGTCTTGGTA
GGTGAAGCTGGTGTCGGTAAGACAGCACTTGCTCTTGGTTTAGCGCAACGTATTGCTTCAGGCGAAGTACCATTTGAATT
GGCTGATATGCGTATCTTAGAGCTTGACATGATGAGCGTTGTTGCAGGGACACGTTTCCGTGGTGATTTCGAAGAGCGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGGAAAATCATTCTCTTTATTGACGAACTACATACGATTATTGGATCT
GGTTCAGGTATTGATAGTACCTTGGATGCGGCTAATATTTTGAAACCGGCCCTTGCGCGCGGGACACTTCACATGGTTGG
AGCAACCACGCAAGCTGAATACCAAAAGCATATTGAGAAAGATGCAGCTTTATCCCGTCGTTTTGCTAAAATTACAATTG
AAGAACCAAGTGTATCTGAAGCAATCGATATTTTAAACGGTTTACGTTCGTCTTATGAAGACTATCATCGTGTGACTATT
ACGGACGCGGCAGTTGAGACGGCAGTCAAGGCAGCGCATCGCTATTTGACGAGTAAGAATTTGCCTGATTCGGCAATTGA
CCTTTTAGATGAAGCGAGTGCAACTGTTCAAGTTCGTATCAAAAAAGAGGACAAACGTGAGATAACGCCTTTGGATGAAG
CACTTATATCTGGGGATATTGGGGCTGCTGTTAAACAGTATAAGGCTAACCAAAAGGCAAAATTTCCTAAACCTGCTTTG
GTAGATGCGGATCAGATTATGCAAACTCTTAGTCGTTTATCAGGTATCCCTGTTGAGAAGATGACGCAGACTGACAGCAA
GCGTTACCTGAATCTTGAATCAGAACTCCACAAACGTGTTATTGGTCAAGATGAGGCGGTTTCGGCTATCAGCCGTGCTA
TTCGTCGTAATCAGTCAGGTATTCGTACTGGAAAACGTCCTATTGGCTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAATTGGCTAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAATCAGCTTTGCTTCGCTTTGATATGTCGGAGTA
TATGGAAAAATTTGCGGCTAGTCGCCTTAATGGTGCTCCTCCAGGGTATGTCGGATATGATGAGGGTGGAGAGTTGACAG
AGAAAGTTCGAAATAAGCCCTACTCAGTTCTTCTCTTTGACGAGATTGAGAAAGCTCATCCAGATATCTTCAACATTCTC
TTACAGGTTTTGGATGACGGTGTTTTAACAGATAGCCGTGGTCGTAAGGTTGATTTTTCAAACACTATCATCATTATGAC
CTCAAATTTGGGAGCTACAGCTCTTCGTGATGATAAAACTGTTGGTTTTGGTGCTCAAACTATTTCTCATAATCACCAAG
CCATGCAAGCACGCATTATGGAAGAGCTTAAGAAGTCCTATCGTCCAGAATTTATTAACCGTATTGATGAGAAGGTTGTC
TTCCACAGCTTAGAGGAAGAACAACTACATGACATTGTCAAGATTATGGTTAAACCATTAATTTCAGCTCTAGCCGATAA
AGGTATAAGCTTAAAATTCCAACCAGCTGCTCTTAAGCATTTGGCTAAGGATGGCTATGATATTGAGATGGGAGCTCGTC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAAGTTGTCTGAGTTATTACTAGGTGGCCAAGTTGTTAGCGGACAG
ACCCTTAAGATTGGTTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (377-454)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-45)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMD-9	100	100	1
clpC	Streptococcus thermophilus LMG 18311	99.387	100	0.994
clpC	Streptococcus mutans UA159	72.549	100	0.725
clpC	Streptococcus pneumoniae TIGR4	66.093	99.755	0.659
clpC	Streptococcus pneumoniae Rx1	66.093	99.755	0.659
clpC	Streptococcus pneumoniae D39	66.093	99.755	0.659
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.542	100	0.515
clpC	Bacillus subtilis subsp. subtilis str. 168	46.65	100	0.469
clpE	Streptococcus mutans UA159	47.764	76.716	0.366