Detailed information NTG0717254

Bioinformatically predicted

Overview

• Name: comGA/cglA
• Type: Machinery gene
• Locus tag: MGCS36089_RS00785
• Genome accession: NZ_CP117284
• Coordinates: 126826..127767 (+)
• Length: 313 a.a.
• NCBI ID: WP_275926236.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGCS36089
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 121826..132767

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS36089_RS00775 (MGCS36089_00316)	rpoC	122536..126177 (+)	3642	WP_037589802.1	DNA-directed RNA polymerase subunit beta'	-
MGCS36089_RS00780 (MGCS36089_00318)	-	126380..126745 (+)	366	WP_003055257.1	DUF1033 family protein	-
MGCS36089_RS00785 (MGCS36089_00320)	comGA/cglA	126826..127767 (+)	942	WP_275926236.1	competence type IV pilus ATPase ComGA	Machinery gene
MGCS36089_RS00790 (MGCS36089_00322)	comGB	127703..128734 (+)	1032	WP_084916952.1	competence type IV pilus assembly protein ComGB	Machinery gene
MGCS36089_RS00795 (MGCS36089_00324)	comGC	128736..129062 (+)	327	WP_084916953.1	competence type IV pilus major pilin ComGC	Machinery gene
MGCS36089_RS00800 (MGCS36089_00326)	comGD	129037..129465 (+)	429	WP_257638821.1	competence type IV pilus minor pilin ComGD	Machinery gene
MGCS36089_RS00805 (MGCS36089_00328)	comGE	129473..129718 (+)	246	WP_049519695.1	competence type IV pilus minor pilin ComGE	Machinery gene
MGCS36089_RS00810 (MGCS36089_00330)	comGF	129699..130139 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
MGCS36089_RS00815 (MGCS36089_00332)	comGG	130162..130491 (+)	330	WP_003058539.1	competence type IV pilus minor pilin ComGG	-
MGCS36089_RS00820 (MGCS36089_00334)	comGH	130554..131507 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
MGCS36089_RS00825 (MGCS36089_00336)	-	131566..132762 (+)	1197	WP_084916957.1	acetate kinase	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 35193.34 Da
• Isoelectric Point: 7.5610

>NTDB_id=717254 MGCS36089_RS00785 WP_275926236.1 126826..127767(+) (comGA/cglA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36089]
MVQALARSILKEAEQIQVQDIYILPKENQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IGGDTLLSLRLSSVGNYRGQESLVIRLLHHQQRSLHYWFDGLKTVARQIGGRGLYLFAGPVGSGKTTLMHQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGVLVFSTVHAKSISGV
YARLLELGVTRAELDNCLALVAYQRLLNGGALIDSTQTEFEHYSPNQWNQKIDDLLAAGHLSPEQARFEKIIQ

Nucleotide

• Length: 942 bp

>NTDB_id=717254 MGCS36089_RS00785 WP_275926236.1 126826..127767(+) (comGA/cglA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36089]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATTCAAGTTCAAGATATCTATATTTTGCCAAAGGA
AAATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGGTGGAGACACACTTTTGTCTCTACGCCTGTCTAGTGTTGGAAATTACCGTGGACAAGAGAGCCTAGTGATTCGGTT
ATTACATCATCAACAAAGAAGTTTACATTACTGGTTTGACGGACTGAAAACAGTTGCACGTCAGATTGGAGGCCGAGGAC
TCTATCTTTTTGCAGGTCCAGTCGGATCAGGCAAAACGACTTTGATGCACCAATTGATTGCTGATTATTATCAAGGAGCA
CAGGTCATTAGCATAGAAGATCCGGTGGAAATTAAAAATCATCAAGCGCTCCAATTACAAGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGTCTTAGTATTTTCAACAGTTCATGCCAAAAGCATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTGGTTGCTTACCAACGATTGCT
TAATGGAGGAGCATTGATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAGAAAATTGATG
ACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (9-267)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	61.613	99.042	0.61
comGA	Streptococcus mutans UA140	61.093	99.361	0.607
comGA	Streptococcus mutans UA159	61.093	99.361	0.607
comGA	Streptococcus gordonii str. Challis substr. CH1	60.45	99.361	0.601
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	59.486	99.361	0.591
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	59.486	99.361	0.591
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	59.486	99.361	0.591
comGA/cglA/cilD	Streptococcus pneumoniae D39	59.486	99.361	0.591
comGA/cglA/cilD	Streptococcus pneumoniae R6	59.486	99.361	0.591
comGA	Lactococcus lactis subsp. cremoris KW2	52.09	99.361	0.518
comGA	Latilactobacillus sakei subsp. sakei 23K	39.249	93.61	0.367