Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   D5070_RS11285 Genome accession   NZ_AP018923
Coordinates   2153902..2154618 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain JMUB3031     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2148902..2159618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D5070_RS11255 (JMUB3031_2089) - 2149118..2149744 (+) 627 WP_000522384.1 nitroreductase family protein -
  D5070_RS11260 (JMUB3031_2090) - 2150105..2150890 (+) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  D5070_RS15395 hld 2151489..2151569 (-) 81 WP_000046023.1 delta-hemolysin -
  D5070_RS11270 (JMUB3031_2092) - 2151859..2152422 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  D5070_RS11275 (JMUB3031_2093) agrD 2152426..2152566 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  D5070_RS11280 (JMUB3031_2094) agrC 2152591..2153883 (+) 1293 WP_172576662.1 quorum-sensing sensor histidine kinase AgrC -
  D5070_RS11285 (JMUB3031_2095) agrA 2153902..2154618 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  D5070_RS11290 - 2154690..2154799 (+) 110 Protein_2091 hypothetical protein -
  D5070_RS11295 (JMUB3031_2096) - 2154987..2155946 (-) 960 WP_117201054.1 carbohydrate kinase family protein -
  D5070_RS11300 (JMUB3031_2097) - 2155943..2157427 (-) 1485 WP_119305761.1 sucrose-6-phosphate hydrolase -
  D5070_RS11305 (JMUB3031_2098) - 2157576..2158526 (-) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=71696 D5070_RS11285 WP_000688492.1 2153902..2154618(+) (agrA) [Staphylococcus aureus strain JMUB3031]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=71696 D5070_RS11285 WP_000688492.1 2153902..2154618(+) (agrA) [Staphylococcus aureus strain JMUB3031]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment