Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   PQQ74_RS04625 Genome accession   NZ_CP117203
Coordinates   959114..960922 (+) Length   602 a.a.
NCBI ID   WP_000082731.1    Uniprot ID   A0A0H2XIW1
Organism   Staphylococcus aureus strain 2022QW-00133     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 954114..965922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQQ74_RS04600 (PQQ74_04600) opp4C 954268..955149 (+) 882 WP_001180262.1 oligopeptide ABC transporter permease -
  PQQ74_RS04605 (PQQ74_04605) trpS 955191..956180 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  PQQ74_RS04610 (PQQ74_04610) spxA 956475..956870 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  PQQ74_RS04615 (PQQ74_04615) mecA 957241..957960 (+) 720 WP_001217730.1 adaptor protein MecA -
  PQQ74_RS04620 (PQQ74_04620) - 958081..959066 (+) 986 Protein_900 competence protein CoiA family protein -
  PQQ74_RS04625 (PQQ74_04625) pepF 959114..960922 (+) 1809 WP_000082731.1 oligoendopeptidase F Regulator
  PQQ74_RS04630 (PQQ74_04630) yjbH 961382..962188 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  PQQ74_RS04635 (PQQ74_04635) - 962211..962576 (-) 366 WP_000214075.1 truncated hemoglobin YjbI -
  PQQ74_RS04640 (PQQ74_04640) - 962680..963273 (-) 594 WP_000224622.1 CYTH domain-containing protein -
  PQQ74_RS04645 (PQQ74_04645) - 963459..963806 (+) 348 WP_001242102.1 hypothetical protein -
  PQQ74_RS04650 (PQQ74_04650) - 963823..964458 (+) 636 WP_001077683.1 GTP pyrophosphokinase family protein -
  PQQ74_RS04655 (PQQ74_04655) - 964475..965284 (+) 810 WP_001270834.1 NAD kinase -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69819.39 Da        Isoelectric Point: 4.9226

>NTDB_id=716834 PQQ74_RS04625 WP_000082731.1 959114..960922(+) (pepF) [Staphylococcus aureus strain 2022QW-00133]
MSQQLSREEQERKYPEYTWDLTTIFKDDEAFEAAFKEVENELGKEEQFKGHIGDSAETLYNALELEDTLGTKLEKVYVYA
HLKQDQDTTNDKYTGMESRAHQLIIKFSSAWSFLVPEILQIDEDKIQSFVNSYDKLQKFAFDLKLINEKRPHILDAETEK
LLTEAQDALSTPSNVYGMFSNADLVFEDAIDKDGNAHPLTQGTFIKYLETDDRKLRESAFRNVYKAYGAHNNTLGATLAG
EVKKNVFNARTHNYKTAREKALSNNHIPENVYDNLVKTVHKYLPLLHRYTELRKELLGLDDLKMYDLYTPLIKDIKFEMP
YEEAKEWMLKALEPMGEEYLNVVKEGLNNRWVDVYENKGKRSGGYSSGAHLTNPFILLNWSNTISDLYTLVHEFGHSAHS
YFSRKFQPSNSSDYTIFVAEVASTCNEALLSDYMDKHLDDEKRLLLLNQELERFRATLFRQTMFAEFEHKIHAIEEAGEP
LTPTRMNEEYAKLNKLYFGDSVETDEDISKEWSRIPHFYMNYYVYQYATGYSAAQSLSHQILTEGKPAVDRYINEFLKKG
SSNYPIEILKNAGVDMTTPEPIEQACEVFEQKLNAFEKLMKA

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=716834 PQQ74_RS04625 WP_000082731.1 959114..960922(+) (pepF) [Staphylococcus aureus strain 2022QW-00133]
ATGAGTCAACAATTATCGAGAGAAGAACAGGAACGTAAATATCCTGAATATACATGGGACTTAACAACAATTTTCAAAGA
TGATGAAGCTTTTGAGGCTGCATTTAAAGAAGTTGAAAATGAGTTAGGCAAAGAAGAACAATTTAAAGGACACATTGGTG
ATAGTGCTGAGACATTATACAATGCGTTAGAATTAGAAGATACATTAGGTACTAAATTAGAAAAAGTATATGTATACGCG
CACCTAAAACAAGACCAAGATACAACGAACGACAAGTATACTGGTATGGAGTCAAGAGCACATCAATTAATTATTAAATT
TAGCTCGGCATGGAGTTTCTTAGTGCCAGAGATTTTACAAATTGATGAAGATAAAATTCAATCATTTGTAAATTCATATG
ATAAATTACAAAAATTCGCATTTGATTTGAAGTTGATTAATGAAAAACGTCCTCATATTTTAGATGCTGAAACTGAAAAG
TTATTAACAGAAGCGCAGGACGCGTTATCAACGCCATCAAATGTATACGGTATGTTTAGCAACGCTGATTTAGTATTTGA
AGATGCGATAGATAAAGATGGAAATGCACACCCGTTAACACAAGGTACATTTATTAAGTATTTAGAAACAGATGATCGCA
AACTAAGAGAAAGTGCTTTTAGAAATGTATATAAAGCATATGGTGCTCATAATAATACGCTTGGCGCTACGCTAGCAGGT
GAAGTGAAGAAAAATGTATTTAATGCTCGTACACACAATTACAAAACTGCAAGAGAAAAAGCATTGAGTAATAATCATAT
TCCAGAAAATGTATATGACAATCTAGTAAAAACTGTACATAAATATTTACCATTGCTACATAGATATACTGAATTGCGCA
AAGAATTGCTAGGTTTAGATGACTTGAAAATGTATGATTTATATACACCATTAATTAAAGATATTAAGTTTGAAATGCCT
TATGAAGAAGCTAAAGAGTGGATGTTAAAAGCATTAGAACCAATGGGTGAAGAATATTTAAATGTAGTTAAAGAAGGCTT
AAACAATCGTTGGGTCGATGTCTATGAGAATAAAGGTAAACGTTCAGGTGGCTATTCATCAGGTGCACATTTAACTAATC
CATTTATTCTACTTAACTGGTCTAATACTATTTCAGACTTATACACATTAGTTCATGAATTTGGGCATTCAGCACATAGT
TACTTCAGTAGAAAATTCCAACCGTCAAATTCTAGTGACTACACTATTTTTGTCGCTGAAGTTGCATCAACTTGTAACGA
AGCACTTTTAAGTGATTATATGGATAAACATCTTGATGATGAAAAACGCTTATTATTATTAAACCAAGAATTAGAACGTT
TCAGAGCTACATTATTCCGACAAACAATGTTCGCAGAATTTGAGCATAAAATTCATGCAATTGAAGAAGCAGGTGAACCA
TTAACGCCAACTAGAATGAATGAAGAATATGCCAAATTAAATAAATTATACTTCGGTGATTCTGTAGAAACTGATGAAGA
TATTAGTAAGGAATGGTCACGTATTCCACACTTCTATATGAATTATTATGTATATCAATACGCAACTGGTTACAGTGCAG
CTCAAAGCTTAAGTCATCAAATTTTAACAGAAGGTAAGCCAGCAGTAGATAGATATATTAATGAATTCTTGAAAAAAGGT
AGCTCAAATTATCCAATTGAGATATTAAAAAATGCTGGTGTAGATATGACAACACCTGAACCAATTGAACAAGCTTGTGA
AGTTTTTGAACAAAAATTGAACGCTTTTGAAAAATTAATGAAAGCTTAG

Domains

Predicted by InterProScan.

Oligopeptidase F (Peptidase_M3_N)

(117-186)

Peptidase family M3 (Peptidase_M3)

(208-587)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XIW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

43.782

97.508

0.427