Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   JMUB1273_RS10440 Genome accession   NZ_AP018922
Coordinates   2027680..2028396 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain JMUB1273     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2022680..2033396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JMUB1273_RS10410 (JMUB1273_1945) - 2022896..2023522 (+) 627 WP_000522384.1 nitroreductase family protein -
  JMUB1273_RS10415 (JMUB1273_1946) - 2023883..2024668 (+) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  JMUB1273_RS14330 hld 2025268..2025348 (-) 81 WP_000046022.1 delta-hemolysin -
  JMUB1273_RS10425 (JMUB1273_1948) agrB 2025638..2026207 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  JMUB1273_RS10430 (JMUB1273_1949) agrD 2026204..2026344 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  JMUB1273_RS10435 (JMUB1273_1950) agrC 2026369..2027661 (+) 1293 WP_172571786.1 quorum-sensing sensor histidine kinase AgrC -
  JMUB1273_RS10440 (JMUB1273_1951) agrA 2027680..2028396 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  JMUB1273_RS10445 - 2028468..2028577 (+) 110 Protein_1946 hypothetical protein -
  JMUB1273_RS10450 (JMUB1273_1952) - 2028765..2029724 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  JMUB1273_RS10455 (JMUB1273_1953) - 2029721..2031205 (-) 1485 WP_000141435.1 sucrose-6-phosphate hydrolase -
  JMUB1273_RS10460 (JMUB1273_1954) - 2031354..2032304 (-) 951 WP_000790326.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=71652 JMUB1273_RS10440 WP_000688498.1 2027680..2028396(+) (agrA) [Staphylococcus aureus strain JMUB1273]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=71652 JMUB1273_RS10440 WP_000688498.1 2027680..2028396(+) (agrA) [Staphylococcus aureus strain JMUB1273]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment