Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NRF13_RS05880 Genome accession   NZ_CP102350
Coordinates   1114473..1115129 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain PMC206     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1109473..1120129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NRF13_RS05855 (NRF13_05855) oppF 1110002..1110919 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  NRF13_RS05860 (NRF13_05860) - 1111026..1112213 (+) 1188 WP_058905933.1 putative glycoside hydrolase -
  NRF13_RS05865 (NRF13_05865) - 1112331..1112909 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  NRF13_RS05870 (NRF13_05870) spx 1113088..1113483 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  NRF13_RS05875 (NRF13_05875) - 1113541..1114197 (-) 657 WP_057080091.1 TerC family protein -
  NRF13_RS05880 (NRF13_05880) mecA 1114473..1115129 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  NRF13_RS05885 (NRF13_05885) - 1115280..1116440 (+) 1161 WP_058905934.1 competence protein CoiA family protein -
  NRF13_RS05890 (NRF13_05890) pepF 1116668..1118497 (+) 1830 WP_024085125.1 oligoendopeptidase F Regulator
  NRF13_RS05895 (NRF13_05895) - 1118535..1118702 (-) 168 WP_003155026.1 hypothetical protein -
  NRF13_RS05900 (NRF13_05900) spxH 1118988..1119890 (-) 903 WP_024085126.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=716327 NRF13_RS05880 WP_003155032.1 1114473..1115129(+) (mecA) [Bacillus velezensis strain PMC206]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=716327 NRF13_RS05880 WP_003155032.1 1114473..1115129(+) (mecA) [Bacillus velezensis strain PMC206]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895