Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   NL412_RS25870 Genome accession   NZ_CP117008
Coordinates   5147410..5148402 (-) Length   330 a.a.
NCBI ID   WP_000224470.1    Uniprot ID   P0ACQ1
Organism   Escherichia coli strain MLI109     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5142410..5153402
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL412_RS25860 (NL412_025855) yieP 5145302..5145994 (+) 693 WP_001131178.1 FadR/GntR family transcriptional regulator -
  NL412_RS25865 (NL412_025860) mdtD 5146017..5147444 (+) 1428 WP_001280852.1 multidrug transporter subunit MdtD -
  NL412_RS25870 (NL412_025865) cytR 5147410..5148402 (-) 993 WP_000224470.1 ribose operon transcriptional repressor RbsR Regulator
  NL412_RS25875 (NL412_025870) rbsK 5148406..5149335 (-) 930 WP_001551941.1 ribokinase -
  NL412_RS25880 (NL412_025875) rbsB 5149461..5150351 (-) 891 WP_001056273.1 ribose ABC transporter substrate-binding protein RbsB -
  NL412_RS25885 (NL412_025880) rbsC 5150376..5151341 (-) 966 WP_000211858.1 ribose ABC transporter permease -
  NL412_RS25890 (NL412_025885) rbsA 5151346..5152851 (-) 1506 WP_001551940.1 ribose ABC transporter ATP-binding protein RbsA -
  NL412_RS25895 (NL412_025890) rbsD 5152859..5153278 (-) 420 WP_000715936.1 D-ribose pyranase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36611.90 Da        Isoelectric Point: 5.2141

>NTDB_id=715970 NL412_RS25870 WP_000224470.1 5147410..5148402(-) (cytR) [Escherichia coli strain MLI109]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=715970 NL412_RS25870 WP_000224470.1 5147410..5148402(-) (cytR) [Escherichia coli strain MLI109]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACCGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCCCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTCGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAACCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACTGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATCGCCTGTATTACCGGCCCGCT
GGATAAAACTCCGGCGCGCCTGAGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCTATGCGCCAACTGTTATCACACCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGCTGTATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACCACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAACCGACCCTTCAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGCGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364