Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   K6K39_RS02770 Genome accession   NZ_AP024135
Coordinates   653912..654565 (-) Length   217 a.a.
NCBI ID   WP_221333942.1    Uniprot ID   A0ABN3C325
Organism   Streptomyces sp. EAS-AB2608 strain NBRC 114648     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 648912..659565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6K39_RS02750 (EASAB2608_00592) - 649335..650600 (-) 1266 WP_059247017.1 right-handed parallel beta-helix repeat-containing protein -
  K6K39_RS02755 (EASAB2608_00593) bla 650799..651647 (-) 849 WP_399010707.1 class A beta-lactamase -
  K6K39_RS02760 (EASAB2608_00594) - 651854..652831 (+) 978 WP_221333941.1 LysR family transcriptional regulator -
  K6K39_RS02765 (EASAB2608_00595) - 652828..653763 (+) 936 WP_059247012.1 serine hydrolase -
  K6K39_RS02770 (EASAB2608_00596) vraR 653912..654565 (-) 654 WP_221333942.1 response regulator transcription factor Regulator
  K6K39_RS02775 (EASAB2608_00597) - 654562..655758 (-) 1197 WP_221335549.1 sensor histidine kinase -
  K6K39_RS02780 (EASAB2608_00598) - 655949..656515 (+) 567 WP_059247008.1 heme-binding protein -
  K6K39_RS02785 (EASAB2608_00599) katG 656634..658856 (-) 2223 WP_086703272.1 catalase/peroxidase HPI -
  K6K39_RS02790 (EASAB2608_00600) - 658890..659327 (-) 438 WP_030640662.1 Fur family transcriptional regulator -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 23239.69 Da        Isoelectric Point: 7.0647

>NTDB_id=71570 K6K39_RS02770 WP_221333942.1 653912..654565(-) (vraR) [Streptomyces sp. EAS-AB2608 strain NBRC 114648]
MTPTPQPPARTPVRILVCDDHAVVRAGLLALLHSAPDIEVVGEAGSGEEALALARKTAPDVVLMDLQLGEGIDGVETTRR
LRAEPPAPHVLVLTTYDTDADVTRAIEAGATGYLLKAERAEDLFTAIQAAAQGRPALSPPVADRVMSRLRNPRPALTPRE
QDILAHLSRGLPNHAIARALYISEATVKTHLRRIYDKLGVDTRAGAVAVAKEQRLLS

Nucleotide


Download         Length: 654 bp        

>NTDB_id=71570 K6K39_RS02770 WP_221333942.1 653912..654565(-) (vraR) [Streptomyces sp. EAS-AB2608 strain NBRC 114648]
ATGACCCCCACCCCGCAGCCGCCCGCACGGACACCGGTGCGCATCCTCGTCTGCGACGACCACGCCGTCGTACGCGCCGG
ACTGCTGGCACTCCTGCACAGCGCACCGGACATCGAGGTGGTCGGCGAGGCCGGCAGCGGCGAGGAGGCGCTCGCCCTCG
CCCGCAAGACCGCCCCGGACGTCGTCCTGATGGACCTGCAGCTCGGCGAGGGCATCGACGGCGTGGAGACCACCCGCCGG
CTGCGCGCCGAACCGCCCGCCCCGCACGTGCTGGTCCTCACCACGTACGACACCGACGCCGACGTCACCCGCGCCATCGA
GGCGGGCGCCACCGGCTATCTGCTGAAGGCCGAGCGTGCCGAGGACCTGTTCACGGCGATCCAGGCCGCCGCCCAGGGCC
GGCCGGCGCTCTCGCCCCCGGTCGCCGACCGGGTCATGTCCCGCCTGCGCAACCCCCGCCCCGCCCTCACCCCGCGGGAG
CAGGACATCCTCGCCCACCTCTCCCGCGGCCTGCCCAACCACGCCATCGCCCGCGCCCTCTACATCAGCGAGGCCACCGT
CAAGACCCACCTCCGCCGCATCTACGACAAGCTGGGAGTGGACACGAGAGCGGGCGCGGTGGCGGTGGCGAAGGAACAAC
GCCTCCTGTCTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-210)

Response regulator receiver domain (Response_reg)

(15-128)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.13

95.392

0.373

Multiple sequence alignment