Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   NQZ90_RS02385 Genome accession   NZ_CP102148
Coordinates   477570..479798 (-) Length   742 a.a.
NCBI ID   WP_015646546.1    Uniprot ID   A0A0M9FFN0
Organism   Streptococcus suis strain DNC15     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 472570..484798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ90_RS02365 (NQZ90_02365) - 472935..473378 (+) 444 WP_015646543.1 GNAT family N-acetyltransferase -
  NQZ90_RS02370 (NQZ90_02370) ileS 473389..476178 (+) 2790 WP_203200632.1 isoleucine--tRNA ligase -
  NQZ90_RS02375 (NQZ90_02375) - 476560..476868 (-) 309 WP_002938710.1 DUF1827 family protein -
  NQZ90_RS02380 (NQZ90_02380) - 476923..477384 (-) 462 WP_024388225.1 NUDIX hydrolase -
  NQZ90_RS02385 (NQZ90_02385) clpE 477570..479798 (-) 2229 WP_015646546.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  NQZ90_RS02390 (NQZ90_02390) - 480021..480251 (+) 231 WP_002938704.1 DUF1797 family protein -
  NQZ90_RS02395 (NQZ90_02395) - 480377..481066 (+) 690 WP_002938702.1 amino acid ABC transporter permease -
  NQZ90_RS02400 (NQZ90_02400) - 481059..481793 (+) 735 WP_002943067.1 amino acid ABC transporter ATP-binding protein -
  NQZ90_RS02405 (NQZ90_02405) - 481923..482771 (+) 849 WP_015646548.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  NQZ90_RS02410 (NQZ90_02410) - 484205..484504 (+) 300 WP_015646549.1 hypothetical protein -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 82596.95 Da        Isoelectric Point: 5.2782

>NTDB_id=714997 NQZ90_RS02385 WP_015646546.1 477570..479798(-) (clpE) [Streptococcus suis strain DNC15]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=714997 NQZ90_RS02385 WP_015646546.1 477570..479798(-) (clpE) [Streptococcus suis strain DNC15]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAACAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCTATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTCTTCAATCACCTAGGTGGCTATCCTGGTAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGGCATAATGGACGTGGAGGACAGACCCCTCCTCCGCAACAACCTCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAATAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCTCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACTATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAAGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTTCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTTCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGATGATGGGCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACCATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACTGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(476-639)

AAA lid domain (AAA_lid_9)

(291-389)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(647-721)

ATPase family associated with various cellular activities (AAA) (AAA)

(153-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FFN0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.361

100

0.837
  clpE Streptococcus pneumoniae D39

82.361

100

0.837
  clpE Streptococcus pneumoniae R6

82.361

100

0.837
  clpE Streptococcus pneumoniae TIGR4

82.361

100

0.837
  clpE Streptococcus mutans UA159

82.377

100

0.832
  clpC Lactococcus lactis subsp. cremoris KW2

77.655

97.709

0.759
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

87.601

0.46
  clpC Streptococcus mutans UA159

48.558

84.097

0.408
  clpC Streptococcus thermophilus LMD-9

48.248

84.636

0.408
  clpC Streptococcus thermophilus LMG 18311

47.93

84.636

0.406
  clpC Streptococcus pneumoniae TIGR4

47.84

84.232

0.403
  clpC Streptococcus pneumoniae Rx1

47.84

84.232

0.403
  clpC Streptococcus pneumoniae D39

47.84

84.232

0.403
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.815

84.636

0.396