Detailed information NTG0714972

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: NQZ91_RS10270
• Genome accession: NZ_CP102145
• Coordinates: 2050405..2052657 (-)
• Length: 750 a.a.
• NCBI ID: WP_105160867.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DNS20
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2045405..2057657

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ91_RS10255 (NQZ91_10255)	-	2048254..2048562 (-)	309	WP_105110199.1	DUF1827 family protein	-
NQZ91_RS10260 (NQZ91_10260)	-	2048625..2049080 (-)	456	WP_105110198.1	NUDIX hydrolase	-
NQZ91_RS10265 (NQZ91_10265)	-	2049237..2050235 (+)	999	WP_257117493.1	MBL fold metallo-hydrolase	-
NQZ91_RS10270 (NQZ91_10270)	clpE	2050405..2052657 (-)	2253	WP_105160867.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NQZ91_RS10275 (NQZ91_10275)	-	2052880..2053110 (+)	231	WP_105123499.1	DUF1797 family protein	-
NQZ91_RS10280 (NQZ91_10280)	-	2053238..2053918 (+)	681	WP_257117494.1	amino acid ABC transporter permease	-
NQZ91_RS10285 (NQZ91_10285)	-	2053920..2054654 (+)	735	WP_257117495.1	amino acid ABC transporter ATP-binding protein	-
NQZ91_RS10290 (NQZ91_10290)	-	2054769..2055614 (+)	846	WP_257117496.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
NQZ91_RS10295 (NQZ91_10295)	-	2056022..2056945 (-)	924	WP_105111906.1	neutral zinc metallopeptidase	-

Sequence

Protein

• Length: 750 a.a.
• Molecular weight: 83226.58 Da
• Isoelectric Point: 5.0535

>NTDB_id=714972 NQZ91_RS10270 WP_105160867.1 2050405..2052657(-) (clpE) [Streptococcus suis strain DNS20]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDFNPNNMDPFSEFFNHLGGYPDNTPAGRDRN
QTPPTQSGGGNRGGGRSNQPGGGIPQAPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPHKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRKEVILFIDEIHEIVGAG
SAGDGNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQAKYQDYHHVKYSD
QAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYK
EMQQATISEEDIPLITEKEIEAIIEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRAQSVLGQLGNFFSPEFMN
RFDGIIEFQPLSKDNLLEIVSLMLEDVNKRLFANGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLE
NPTEKNLRAVMSSKGDIQIKAQTVAKVKEV

Nucleotide

• Length: 2253 bp

>NTDB_id=714972 NQZ91_RS10270 WP_105160867.1 2050405..2052657(-) (clpE) [Streptococcus suis strain DNS20]
ATGCTCTGCAAAAACTGTAACATCAATGACGCAACCATCCATCTCTACACCAACCTCAACGGCAAACAACAGCAGGTCGA
CCTCTGCCACAACTGCTACCAAATCATGAAGACTGACCCCAACAACGCCATTCTCCGTGGCCTAGGCGACTTCAACCCTA
ACAACATGGATCCCTTCAGTGAATTTTTCAATCATTTGGGAGGATACCCTGACAACACACCAGCTGGACGTGACCGCAAC
CAGACACCTCCGACCCAGTCTGGAGGAGGGAACCGAGGCGGCGGCCGCTCCAATCAGCCTGGCGGAGGTATCCCGCAAGC
ACCGCAACAGCCAAACGGCCTCTTGGAAGAATTTGGTATTAACGTGACCGAGATTGCTCGTCGTGGAGATATTGACCCGG
TTATCGGACGCGACCAAGAAATCACTCGCGTAATTGAGATTCTCAACCGCCGGACCAAGAACAACCCCGTCCTCATCGGT
GAGCCCGGTGTTGGTAAAACGGCCGTTGTCGAAGGTCTGGCCCAGAAAATCGTAGACGGAGATGTCCCACATAAACTCCA
AAATAAGGAAGTTATCCGCCTAGACGTTGTTAGCTTAGTGCAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGC
AAAAACTAATGGAGGAAATTCGCAACCGTAAGGAAGTCATCCTCTTTATCGACGAAATCCATGAAATTGTCGGAGCAGGT
TCTGCTGGCGACGGCAACATGGATGCCGGCAACATTCTCAAACCAGCTCTTGCCCGTGGCGAAATGCAACTGGTCGGAGC
AACCACCCTCAATGAATATCGTATTATCGAGAAGGACGCCGCCTTGGAACGCCGCATGCAACCTGTCAAGGTTGAGGAGC
CAAGCGTCGAAGAGACCATTACCATTCTCAAGGGCATCCAGGCTAAGTACCAGGACTACCACCACGTTAAGTATTCAGAT
CAGGCTATTGAAGCTGCAGCTGTCCTTTCCAACCGCTACATCCAGGACCGATTCCTGCCTGACAAGGCCATTGACCTCTT
GGATGAGGCGGGTTCCAAGATGAACCTGACTCTCAATTTCATTGATCCGAAAGAGATTGACCAACGCCTGATCGATGCTG
AAAATCGCAAAGCCCAGGCTACTCGTGATGAAGACTACGAAAAAGCTGCTTACTTCCGCGACCAGATTGCTAAATACAAG
GAAATGCAGCAGGCGACTATCAGTGAAGAGGACATTCCACTCATTACTGAGAAGGAAATTGAGGCCATTATCGAGCAGAA
AACCAATATTCCTGTCGGCGATTTGAAGGAGAAAGAACAATCTCAACTCATCAACCTAGCTAGCGACCTCAAGGCTCATG
TGATTGGCCAAGACGATGCCGTGGATAAGATTGCCAAGGCCATTCGTCGCAATCGCGTCGGATTGGGTGCGCCCAACCGT
CCAATCGGTTCCTTCCTTTTCGTTGGTCCAACCGGTGTCGGTAAGACCGAGCTTTCTAAACAGCTGGCCATCGAGCTCTT
CGGCTCAGCTGATAGTATGATTCGCTTTGATATGTCTGAGTACATGGAAAAACACGCCGTTGCCAAATTGGTCGGTGCCC
CTCCAGGCTATGTCGGCTATGAAGAGGCCGGGCAATTGACTGAGAAAGTGCGCCGCAATCCCTACTCGCTCATTCTCCTG
GATGAGGTAGAAAAGGCCCATCCAGATGTCATGCACATGTTCTTGCAGGTCCTGGATGACGGTCGCTTGACAGACGGGCA
AGGTCGGACTGTTTCCTTCAAAGATACTATCATTATCATGACCTCCAATGCCGGTACTGGCAAGGTTGAGGCCTCTGTCG
GTTTCGGTGCTGCTATGGAAGGGCGGGCTCAATCAGTCCTCGGTCAGCTTGGTAACTTCTTCAGCCCAGAATTTATGAAC
CGTTTCGACGGTATCATCGAATTCCAGCCGCTTAGTAAGGATAATCTGCTTGAAATTGTCAGCCTCATGCTGGAAGATGT
CAACAAGCGCTTGTTTGCCAACGGCATCAGCCTCCATGTGACAGACAAGGTCAAGGAAAAATTGGTCGACCTGGGCTATG
ATCCAAAAATGGGTGCCCGTCCGCTCCGACGAACCATTCAAGACCAGATTGAAGATGCTATCACGGACTTCTATCTGGAA
AATCCAACGGAGAAAAATCTTCGCGCTGTCATGTCCAGCAAGGGAGACATTCAGATTAAGGCGCAAACCGTCGCCAAAGT
CAAAGAAGTCTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (157-276)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-726)

• AAA lid domain (AAA_lid_9) (295-393)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.979	100	0.832
clpE	Streptococcus pneumoniae D39	82.979	100	0.832
clpE	Streptococcus pneumoniae R6	82.979	100	0.832
clpE	Streptococcus pneumoniae TIGR4	82.979	100	0.832
clpE	Streptococcus mutans UA159	82.557	100	0.827
clpC	Lactococcus lactis subsp. cremoris KW2	77.038	98.133	0.756
clpC	Bacillus subtilis subsp. subtilis str. 168	50.523	89.2	0.451
clpC	Streptococcus pneumoniae D39	48	83.333	0.4
clpC	Streptococcus pneumoniae Rx1	48	83.333	0.4
clpC	Streptococcus pneumoniae TIGR4	48	83.333	0.4
clpC	Streptococcus mutans UA159	48.154	83.067	0.4
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.719	85.333	0.399
clpC	Streptococcus thermophilus LMD-9	47.293	83.733	0.396
clpC	Streptococcus thermophilus LMG 18311	46.975	83.733	0.393