Detailed information NTG0714948

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: NQZ91_RS07595
• Genome accession: NZ_CP102145
• Coordinates: 1515225..1515959 (+)
• Length: 244 a.a.
• NCBI ID: WP_257117255.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DNS20
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1510225..1520959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ91_RS07570 (NQZ91_07570)	pcsB	1510429..1511682 (+)	1254	WP_105122066.1	peptidoglycan hydrolase PcsB	-
NQZ91_RS07575 (NQZ91_07575)	-	1511780..1512745 (+)	966	WP_105122067.1	ribose-phosphate diphosphokinase	-
NQZ91_RS07580 (NQZ91_07580)	-	1512841..1514019 (+)	1179	WP_105111632.1	pyridoxal phosphate-dependent aminotransferase	-
NQZ91_RS07585 (NQZ91_07585)	recO	1514006..1514770 (+)	765	WP_257117253.1	DNA repair protein RecO	-
NQZ91_RS07590 (NQZ91_07590)	-	1514782..1515123 (-)	342	WP_257117254.1	hypothetical protein	-
NQZ91_RS07595 (NQZ91_07595)	comE/blpR	1515225..1515959 (+)	735	WP_257117255.1	response regulator transcription factor	Regulator
NQZ91_RS07600 (NQZ91_07600)	-	1516151..1517320 (+)	1170	WP_257117256.1	sensor histidine kinase	-
NQZ91_RS07605 (NQZ91_07605)	-	1517643..1518377 (+)	735	WP_257117257.1	hypothetical protein	-
NQZ91_RS07610 (NQZ91_07610)	-	1518405..1519280 (+)	876	WP_257117258.1	ABC transporter ATP-binding protein	-
NQZ91_RS07615 (NQZ91_07615)	-	1519282..1520052 (+)	771	WP_257117260.1	hypothetical protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28072.05 Da
• Isoelectric Point: 5.2193

>NTDB_id=714948 NQZ91_RS07595 WP_257117255.1 1515225..1515959(+) (comE/blpR) [Streptococcus suis strain DNS20]
MLRIFILEDDFMQQARLEQAIEEAVKTSDVVYKTLEVFGKPQQLLEAVTETGNHQLFFLDIEIRGEEKKGMEIAREIRTR
DPHAVIVFVTTHSEFMPLTYKYRVSALDFIDKGLEESAFKEAVADVLQHAYDHISQTVSDDSFVFKSEFSQIQVPFSDIL
YFETSSTPHKVVLTTKSGHMEFYGKVSDIAKTDGRLYQSHRAFVVNPANILRVDAVERMVYFEQEESCLVSRMKLKGLLE
RVGK

Nucleotide

• Length: 735 bp

>NTDB_id=714948 NQZ91_RS07595 WP_257117255.1 1515225..1515959(+) (comE/blpR) [Streptococcus suis strain DNS20]
ATGTTACGGATTTTTATCTTGGAAGATGATTTTATGCAACAAGCTAGGTTGGAGCAGGCGATTGAGGAAGCTGTAAAAAC
GAGTGACGTTGTCTATAAGACCTTAGAAGTGTTTGGTAAACCTCAGCAGTTATTGGAGGCTGTGACAGAGACTGGAAATC
ATCAGCTCTTTTTCCTAGATATTGAGATTAGAGGTGAGGAGAAGAAAGGGATGGAGATTGCACGGGAGATTCGGACGCGT
GATCCACATGCTGTAATTGTCTTTGTGACGACACATTCGGAATTTATGCCTTTGACCTATAAGTACCGTGTGTCAGCTCT
TGATTTTATTGATAAGGGGCTGGAAGAATCAGCTTTCAAGGAAGCGGTGGCGGATGTTCTCCAACATGCTTACGATCATA
TCAGCCAGACAGTGAGTGATGATTCTTTTGTCTTCAAGAGTGAGTTTTCTCAGATTCAGGTGCCGTTTTCAGATATTTTG
TATTTTGAAACCTCTTCAACACCTCATAAGGTCGTCTTGACAACCAAGTCAGGTCATATGGAGTTTTATGGCAAGGTGTC
AGATATTGCAAAAACGGATGGACGTTTGTACCAGAGCCATCGGGCTTTTGTGGTCAATCCTGCTAATATTCTTCGTGTGG
ATGCTGTGGAGCGGATGGTGTATTTTGAACAGGAGGAATCTTGCTTGGTCTCTCGAATGAAACTGAAAGGTTTGCTGGAA
AGGGTAGGGAAATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (152-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	55.649	97.951	0.545
comE/comE1	Streptococcus equinus JB1	46.025	97.951	0.451
comE/comE2	Streptococcus equinus JB1	39.916	97.541	0.389
comE	Streptococcus infantis strain Atu-4	36.905	100	0.381
comE	Streptococcus pneumoniae TIGR4	37.805	100	0.381
comE	Streptococcus mitis NCTC 12261	37.805	100	0.381
comE	Streptococcus pneumoniae D39	37.805	100	0.381
comE	Streptococcus pneumoniae R6	37.805	100	0.381
comE	Streptococcus mitis SK321	37.805	100	0.381
comE	Streptococcus pneumoniae Rx1	37.805	100	0.381
comE/comE2	Streptococcus gordonii strain NCTC7865	37.449	99.59	0.373
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.449	99.59	0.373