Detailed information NTG0714911

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NQZ92_RS08650
• Genome accession: NZ_CP102143
• Coordinates: 1704350..1705399 (-)
• Length: 349 a.a.
• NCBI ID: WP_009910567.1
• Uniprot ID: A0A7Y6RPS3
• Organism: Streptococcus suis strain DNR43
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1699350..1710399

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ92_RS08630 (NQZ92_08630)	nadE	1700288..1701112 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
NQZ92_RS08635 (NQZ92_08635)	-	1701876..1702403 (-)	528	WP_004194600.1	VanZ family protein	-
NQZ92_RS08640 (NQZ92_08640)	rlmN	1702400..1703512 (-)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NQZ92_RS08645 (NQZ92_08645)	-	1703521..1704162 (-)	642	WP_004194595.1	YutD-like domain-containing protein	-
NQZ92_RS08650 (NQZ92_08650)	sepM	1704350..1705399 (-)	1050	WP_009910567.1	SepM family pheromone-processing serine protease	Regulator
NQZ92_RS08655 (NQZ92_08655)	coaD	1705386..1705874 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
NQZ92_RS08660 (NQZ92_08660)	rsmD	1705864..1706403 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NQZ92_RS08665 (NQZ92_08665)	-	1706702..1707424 (-)	723	WP_013730502.1	hypothetical protein	-
NQZ92_RS08670 (NQZ92_08670)	-	1707481..1707867 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NQZ92_RS08675 (NQZ92_08675)	-	1707867..1708085 (-)	219	WP_004194736.1	YqgQ family protein	-
NQZ92_RS08680 (NQZ92_08680)	-	1708385..1708987 (-)	603	WP_004194738.1	response regulator transcription factor	-
NQZ92_RS08685 (NQZ92_08685)	-	1708984..1710078 (-)	1095	WP_024394990.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37733.77 Da
• Isoelectric Point: 4.6112

>NTDB_id=714911 NQZ92_RS08650 WP_009910567.1 1704350..1705399(-) (sepM) [Streptococcus suis strain DNR43]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLVKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=714911 NQZ92_RS08650 WP_009910567.1 1704350..1705399(-) (sepM) [Streptococcus suis strain DNR43]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGGTTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A7Y6RPS3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.519	99.427	0.602