Detailed information NTG0714697

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NQZ96_RS07755
• Genome accession: NZ_CP102137
• Coordinates: 1573812..1574861 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain M104300_S20
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1568812..1579861

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ96_RS07735 (NQZ96_07735)	nadE	1569218..1570042 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
NQZ96_RS07740 (NQZ96_07740)	-	1571338..1571865 (-)	528	WP_012027591.1	VanZ family protein	-
NQZ96_RS07745 (NQZ96_07745)	rlmN	1571862..1572974 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NQZ96_RS07750 (NQZ96_07750)	-	1572983..1573624 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
NQZ96_RS07755 (NQZ96_07755)	sepM	1573812..1574861 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
NQZ96_RS07760 (NQZ96_07760)	coaD	1574848..1575336 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
NQZ96_RS07765 (NQZ96_07765)	rsmD	1575326..1575865 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NQZ96_RS07770 (NQZ96_07770)	-	1576173..1576895 (-)	723	WP_012027598.1	lipoprotein	-
NQZ96_RS07775 (NQZ96_07775)	-	1576952..1577338 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NQZ96_RS07780 (NQZ96_07780)	-	1577338..1577556 (-)	219	WP_004194736.1	YqgQ family protein	-
NQZ96_RS07785 (NQZ96_07785)	-	1577864..1578466 (-)	603	WP_012027601.1	response regulator transcription factor	-
NQZ96_RS07790 (NQZ96_07790)	-	1578463..1579557 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=714697 NQZ96_RS07755 WP_012775295.1 1573812..1574861(-) (sepM) [Streptococcus suis strain M104300_S20]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=714697 NQZ96_RS07755 WP_012775295.1 1573812..1574861(-) (sepM) [Streptococcus suis strain M104300_S20]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605