Detailed information NTG0714572

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: NQZ98_RS03205
• Genome accession: NZ_CP102135
• Coordinates: 599535..601763 (-)
• Length: 742 a.a.
• NCBI ID: WP_257116672.1
• Uniprot ID: -
• Organism: Streptococcus suis strain M106471_S40
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 594535..606763

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ98_RS03185 (NQZ98_03185)	-	595047..595490 (+)	444	WP_024411798.1	GNAT family N-acetyltransferase	-
NQZ98_RS03190 (NQZ98_03190)	ileS	595501..598290 (+)	2790	WP_024411797.1	isoleucine--tRNA ligase	-
NQZ98_RS03195 (NQZ98_03195)	-	598526..598834 (-)	309	WP_002938710.1	DUF1827 family protein	-
NQZ98_RS03200 (NQZ98_03200)	-	598889..599350 (-)	462	WP_024399534.1	NUDIX hydrolase	-
NQZ98_RS03205 (NQZ98_03205)	clpE	599535..601763 (-)	2229	WP_257116672.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NQZ98_RS03210 (NQZ98_03210)	-	601987..602217 (+)	231	WP_002938704.1	DUF1797 family protein	-
NQZ98_RS03215 (NQZ98_03215)	-	602343..603032 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
NQZ98_RS03220 (NQZ98_03220)	-	603025..603759 (+)	735	WP_002943067.1	amino acid ABC transporter ATP-binding protein	-
NQZ98_RS03225 (NQZ98_03225)	-	603889..604737 (+)	849	WP_024385039.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
NQZ98_RS03230 (NQZ98_03230)	-	606171..606470 (+)	300	WP_015646549.1	hypothetical protein	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82576.92 Da
• Isoelectric Point: 5.3441

>NTDB_id=714572 NQZ98_RS03205 WP_257116672.1 599535..601763(-) (clpE) [Streptococcus suis strain M106471_S40]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFINPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLHAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=714572 NQZ98_RS03205 WP_257116672.1 599535..601763(-) (clpE) [Streptococcus suis strain M106471_S40]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCTATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAATCCTGTTCTTATCGGTGAGCCTGGGGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAAAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATTATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACTATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTAATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAAGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTTCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACCATCATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGC
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACATGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

• ATPase family associated with various cellular activities (AAA) (AAA) (153-272)

• AAA lid domain (AAA_lid_9) (291-389)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.228	100	0.836
clpE	Streptococcus pneumoniae D39	82.228	100	0.836
clpE	Streptococcus pneumoniae R6	82.228	100	0.836
clpE	Streptococcus pneumoniae TIGR4	82.228	100	0.836
clpE	Streptococcus mutans UA159	82.243	100	0.83
clpC	Lactococcus lactis subsp. cremoris KW2	77.517	97.709	0.757
clpC	Bacillus subtilis subsp. subtilis str. 168	52.615	87.601	0.461
clpC	Streptococcus mutans UA159	48.558	84.097	0.408
clpC	Streptococcus thermophilus LMD-9	48.089	84.636	0.407
clpC	Streptococcus thermophilus LMG 18311	47.93	84.636	0.406
clpC	Streptococcus pneumoniae TIGR4	47.84	84.232	0.403
clpC	Streptococcus pneumoniae Rx1	47.84	84.232	0.403
clpC	Streptococcus pneumoniae D39	47.84	84.232	0.403
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.815	84.636	0.396