Detailed information NTG0714293

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: NQZ84_RS02470
• Genome accession: NZ_CP102094
• Coordinates: 488720..490939 (-)
• Length: 739 a.a.
• NCBI ID: WP_257049312.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 12RC1
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 483720..495939

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ84_RS02450 (NQZ84_02450)	-	484087..484530 (+)	444	WP_172070630.1	GNAT family N-acetyltransferase	-
NQZ84_RS02455 (NQZ84_02455)	ileS	484541..487330 (+)	2790	WP_257049315.1	isoleucine--tRNA ligase	-
NQZ84_RS02460 (NQZ84_02460)	-	487710..488018 (-)	309	WP_002938710.1	DUF1827 family protein	-
NQZ84_RS02465 (NQZ84_02465)	-	488073..488534 (-)	462	WP_002938708.1	NUDIX hydrolase	-
NQZ84_RS02470 (NQZ84_02470)	clpE	488720..490939 (-)	2220	WP_257049312.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NQZ84_RS02475 (NQZ84_02475)	-	491163..491393 (+)	231	WP_002938704.1	DUF1797 family protein	-
NQZ84_RS02480 (NQZ84_02480)	-	491519..492208 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
NQZ84_RS02485 (NQZ84_02485)	-	492201..492935 (+)	735	WP_002943067.1	amino acid ABC transporter ATP-binding protein	-
NQZ84_RS02490 (NQZ84_02490)	-	493065..493913 (+)	849	WP_044769449.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-

Sequence

Protein

• Length: 739 a.a.
• Molecular weight: 82224.56 Da
• Isoelectric Point: 5.3491

>NTDB_id=714293 NQZ84_RS02470 WP_257049312.1 488720..490939(-) (clpE) [Streptococcus suis strain 12RC1]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVNGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGDGNM
DAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIEAAA
VLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQKATI
SEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYIEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVEKAH
PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDGIIE
FQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAEKDL
RAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2220 bp

>NTDB_id=714293 NQZ84_RS02470 WP_257049312.1 488720..490939(-) (clpE) [Streptococcus suis strain 12RC1]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCAAATGGGCT
CCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCGATCAAGAAA
TTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTAGGTAAAACA
GCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCAATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGTCATTCGTCT
GGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGGAAGAAATCC
GTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGATGGTAACATG
GATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAACGAGTACCG
TATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAGAAACCATTA
CCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAAGCTGCCGCG
GTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTAGATGAAGCTGGTTCAAAAAT
GAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAGCACAAGCTA
CACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAGGCAACTATC
AGCGAGGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCCAGTTGGTGA
TTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAGATGAAGCAG
TTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGCTCCTTCCTCTTT
GTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGACAGCATGAT
CCGCTTCGACATGTCCGAATACATAGAAAAACATGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATGTAGGCTATG
AGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAAAAAGCCCAC
CCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGTCGGACAGTCAGCTTCAA
AGATACTATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGGCTATGGAAG
GGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGTATTATTGAG
TTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCTTTCTCACAA
TGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGGGAGCTCGTC
CACTACGCAGAACTATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAAAAAGACCTA
CGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (288-386)

• AAA domain (Cdc48 subfamily) (AAA_2) (473-636)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (644-718)

• ATPase family associated with various cellular activities (AAA) (AAA) (150-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.423	100	0.838
clpE	Streptococcus pneumoniae D39	82.423	100	0.838
clpE	Streptococcus pneumoniae R6	82.423	100	0.838
clpE	Streptococcus pneumoniae TIGR4	82.423	100	0.838
clpE	Streptococcus mutans UA159	81.976	100	0.831
clpC	Lactococcus lactis subsp. cremoris KW2	77.701	97.7	0.759
clpC	Bacillus subtilis subsp. subtilis str. 168	50.583	92.828	0.47
clpC	Streptococcus pneumoniae D39	46.646	88.769	0.414
clpC	Streptococcus pneumoniae TIGR4	46.646	88.769	0.414
clpC	Streptococcus pneumoniae Rx1	46.646	88.769	0.414
clpC	Streptococcus thermophilus LMD-9	47.196	86.874	0.41
clpC	Streptococcus mutans UA159	48.315	84.303	0.407
clpC	Streptococcus thermophilus LMG 18311	46.885	86.874	0.407
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.815	84.98	0.398