Detailed information NTG0714008

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NQD65_RS02905
• Genome accession: NZ_CP101996
• Coordinates: 508517..509590 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain BCJB1835
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 503517..514590

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQD65_RS02875 (NQD65_02885)	-	504410..505474 (+)	1065	WP_000021309.1	MmcQ/YjbR family DNA-binding protein	-
NQD65_RS02880 (NQD65_02890)	asnA	505588..506580 (+)	993	WP_000748017.1	aspartate--ammonia ligase	-
NQD65_RS02885 (NQD65_02895)	-	506625..507074 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
NQD65_RS02890 (NQD65_02900)	rsmD	507204..507743 (+)	540	WP_001266830.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NQD65_RS02895 (NQD65_02905)	-	507755..508045 (+)	291	WP_000384889.1	hypothetical protein	-
NQD65_RS02900 (NQD65_02910)	coaD	508042..508527 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
NQD65_RS02905 (NQD65_02915)	sepM	508517..509590 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
NQD65_RS02910 (NQD65_02920)	-	509665..510997 (+)	1333	Protein_489	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
NQD65_RS02915 (NQD65_02925)	-	511066..511644 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
NQD65_RS02920 (NQD65_02930)	rlmN	511695..512801 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NQD65_RS02925 (NQD65_02935)	-	512801..513316 (+)	516	WP_000919802.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=714008 NQD65_RS02905 WP_000796095.1 508517..509590(+) (sepM) [Streptococcus agalactiae strain BCJB1835]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=714008 NQD65_RS02905 WP_000796095.1 508517..509590(+) (sepM) [Streptococcus agalactiae strain BCJB1835]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658