Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   NPS17_RS06310 Genome accession   NZ_CP101985
Coordinates   1368722..1369615 (+) Length   297 a.a.
NCBI ID   WP_002272311.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14R     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1363722..1374615
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS17_RS06290 (NPS17_06290) - 1365687..1365815 (-) 129 WP_258968832.1 hypothetical protein -
  NPS17_RS06295 (NPS17_06295) - 1365850..1366080 (-) 231 WP_002282891.1 hypothetical protein -
  NPS17_RS06300 (NPS17_06300) - 1366210..1367961 (-) 1752 WP_002272312.1 GbpC/Spa domain-containing protein -
  NPS17_RS06305 (NPS17_06305) - 1368122..1368406 (-) 285 WP_258968833.1 helix-turn-helix transcriptional regulator -
  NPS17_RS06310 (NPS17_06310) irvR 1368722..1369615 (+) 894 WP_002272311.1 LexA family transcriptional regulator IrvR Regulator
  NPS17_RS06315 (NPS17_06315) - 1371278..1371655 (-) 378 WP_032526274.1 type II toxin-antitoxin system HicB family antitoxin -
  NPS17_RS06320 (NPS17_06320) - 1371673..1371864 (-) 192 WP_002290797.1 type II toxin-antitoxin system HicA family toxin -
  NPS17_RS06325 (NPS17_06325) csn2 1371961..1372623 (-) 663 WP_258968834.1 type II-A CRISPR-associated protein Csn2 -
  NPS17_RS06330 (NPS17_06330) cas2 1372613..1372957 (-) 345 WP_002263547.1 CRISPR-associated endonuclease Cas2 -
  NPS17_RS06335 (NPS17_06335) cas1 1372954..1373820 (-) 867 WP_014677910.1 type II CRISPR-associated endonuclease Cas1 -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33625.32 Da        Isoelectric Point: 6.7036

>NTDB_id=713581 NPS17_RS06310 WP_002272311.1 1368722..1369615(+) (irvR) [Streptococcus mutans strain COCC33-14R]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTDDKVADKSNHTQYQKVVDSFIAKELNDQTI
IHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALTVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=713581 NPS17_RS06310 WP_002272311.1 1368722..1369615(+) (irvR) [Streptococcus mutans strain COCC33-14R]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCAATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCCACTATCCTTAACATTCCTACAAGTAGTCTTAATGAATATGTTAAAGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTCTCCAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAGGAACAAGATGAAACAGCAAGCTTATCTGCCAGTGATGAAACGACTGATGATAAAG
TTGCTGACAAATCAAATCATACGCAGTATCAAAAGGTTGTTGATTCTTTTATTGCCAAAGAATTAAACGATCAGACAATT
ATTCATTGGGATAATGTGATAAAAGCTAAGGATTTGTATCAAACCTTTGGACGTCAATACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTACTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(22-70)

Peptidase S24-like (Peptidase_S24)

(184-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

99.327

100

0.993