Detailed information    

insolico Bioinformatically predicted

Overview

Name   hdrM   Type   Regulator
Locus tag   NPS18_RS08650 Genome accession   NZ_CP101984
Coordinates   1754070..1754756 (+) Length   228 a.a.
NCBI ID   WP_002262670.1    Uniprot ID   -
Organism   Streptococcus mutans strain UA-159     
Function   repress competence development; negative regulate HdrR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1749070..1759756
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS08630 (NPS18_08630) - 1751069..1751290 (+) 222 WP_019313410.1 hypothetical protein -
  NPS18_RS08635 (NPS18_08635) - 1751690..1752634 (+) 945 WP_002262667.1 magnesium transporter CorA family protein -
  NPS18_RS08640 (NPS18_08640) - 1752916..1753578 (+) 663 WP_002262668.1 DUF1129 domain-containing protein -
  NPS18_RS08645 (NPS18_08645) hdrR 1753717..1754073 (+) 357 WP_002262669.1 LytTR family transcriptional regulator HdrR Regulator
  NPS18_RS08650 (NPS18_08650) hdrM 1754070..1754756 (+) 687 WP_002262670.1 hdrR negative regulator HdrM Regulator
  NPS18_RS08655 (NPS18_08655) - 1754764..1755483 (-) 720 WP_002262671.1 TraX family protein -
  NPS18_RS08660 (NPS18_08660) rpsR 1755802..1756041 (-) 240 WP_000068664.1 30S ribosomal protein S18 -
  NPS18_RS08665 (NPS18_08665) ssbA 1756070..1756564 (-) 495 WP_002261867.1 single-stranded DNA-binding protein Machinery gene
  NPS18_RS08670 (NPS18_08670) rpsF 1756582..1756872 (-) 291 WP_002261866.1 30S ribosomal protein S6 -
  NPS18_RS08675 (NPS18_08675) - 1757028..1757273 (-) 246 WP_002263367.1 hypothetical protein -
  NPS18_RS08680 (NPS18_08680) - 1757578..1757781 (+) 204 WP_002263366.1 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26110.18 Da        Isoelectric Point: 6.8478

>NTDB_id=713518 NPS18_RS08650 WP_002262670.1 1754070..1754756(+) (hdrM) [Streptococcus mutans strain UA-159]
MKKNYFWYGLLGLLALYLITIAFIPGFHIFFSNMLMLALFFMLIALSNRSIFFFFLALGFLSIYLKDIFHFDYSTGPLFT
GIIIIGVILNSFLKPHYSYSYKGNHYFNMKQHANYIDNETDVFLKTLFSENTSYVTSQELNKIIIDTKFGEQSVDLSQAQ
FMTDSPEIHIDVSFGETNLRIPNNWKIINKTHSPFASISFSGFPSTNGDFINVTLTGTVAMGSLNIQY

Nucleotide


Download         Length: 687 bp        

>NTDB_id=713518 NPS18_RS08650 WP_002262670.1 1754070..1754756(+) (hdrM) [Streptococcus mutans strain UA-159]
ATGAAAAAAAATTATTTTTGGTACGGTCTGCTTGGGCTTCTCGCACTTTACCTTATTACTATTGCTTTTATCCCGGGATT
TCATATTTTCTTTAGCAACATGTTGATGTTGGCCCTGTTCTTTATGTTAATAGCTTTGAGTAACAGGAGTATCTTCTTTT
TCTTTCTAGCCTTAGGTTTTCTTAGTATCTACTTGAAAGATATCTTTCATTTTGACTATTCTACCGGACCGCTTTTTACG
GGTATAATCATTATCGGCGTTATTTTAAACAGTTTCCTCAAACCACACTATTCTTATTCTTATAAAGGAAATCATTATTT
TAATATGAAACAACATGCTAACTACATTGATAACGAAACAGATGTCTTTTTAAAAACACTTTTTTCTGAAAATACCAGTT
ATGTGACTTCTCAAGAATTAAATAAAATTATTATTGATACTAAGTTTGGAGAACAATCTGTTGATCTCTCTCAAGCTCAA
TTTATGACAGATTCTCCCGAAATTCATATAGATGTTAGCTTTGGTGAAACCAATCTGCGTATTCCAAACAACTGGAAAAT
CATCAATAAAACTCACTCCCCCTTTGCTTCCATTTCATTTTCAGGTTTTCCTAGCACAAATGGTGATTTTATTAACGTTA
CATTGACTGGAACAGTGGCTATGGGATCTCTAAACATTCAATATTAA

Domains

Predicted by InterProScan.

Cell wall-active antibiotics response 4TMS YvqF (LiaF-like_C)

(128-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hdrM Streptococcus mutans UA159

100

100

1