Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   NPS18_RS06490 Genome accession   NZ_CP101984
Coordinates   1328082..1328975 (+) Length   297 a.a.
NCBI ID   WP_002262721.1    Uniprot ID   A0A090B2L0
Organism   Streptococcus mutans strain UA-159     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1323082..1333975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS06470 (NPS18_06470) - 1325045..1325173 (-) 129 WP_002262718.1 hypothetical protein -
  NPS18_RS06475 (NPS18_06475) - 1325208..1325438 (-) 231 WP_002282891.1 hypothetical protein -
  NPS18_RS06480 (NPS18_06480) - 1325568..1327319 (-) 1752 WP_002262719.1 GbpC/Spa domain-containing protein -
  NPS18_RS06485 (NPS18_06485) - 1327482..1327767 (-) 286 Protein_1248 helix-turn-helix transcriptional regulator -
  NPS18_RS06490 (NPS18_06490) irvR 1328082..1328975 (+) 894 WP_002262721.1 LexA family transcriptional regulator IrvR Regulator
  NPS18_RS06495 (NPS18_06495) - 1329644..1330021 (-) 378 WP_002263544.1 type II toxin-antitoxin system HicB family antitoxin -
  NPS18_RS06500 (NPS18_06500) - 1330039..1330230 (-) 192 WP_002263545.1 type II toxin-antitoxin system HicA family toxin -
  NPS18_RS06505 (NPS18_06505) csn2 1330327..1330989 (-) 663 WP_002263546.1 type II-A CRISPR-associated protein Csn2 -
  NPS18_RS06510 (NPS18_06510) cas2 1330979..1331323 (-) 345 WP_002263547.1 CRISPR-associated endonuclease Cas2 -
  NPS18_RS06515 (NPS18_06515) cas1 1331320..1332186 (-) 867 WP_002352326.1 type II CRISPR-associated endonuclease Cas1 -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33651.40 Da        Isoelectric Point: 6.7038

>NTDB_id=713506 NPS18_RS06490 WP_002262721.1 1328082..1328975(+) (irvR) [Streptococcus mutans strain UA-159]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTEDKVADKSNHTQYQKVVDSFIAKELNDQTI
IHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALIVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=713506 NPS18_RS06490 WP_002262721.1 1328082..1328975(+) (irvR) [Streptococcus mutans strain UA-159]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCAATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCTACTATTCTTAACATTCCTACAAGTAGTCTTAACGAATATGTTAAGGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTTTACAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAAGAACAAGATGAAACAGCAAGCTTGTCTGCCAGTGATGAAACGACTGAGGATAAAG
TTGCTGACAAATCAAATCATACGCAGTATCAAAAGGTTGTTGATTCTTTTATTGCCAAAGAATTAAACGATCAGACAATT
ATTCATTGGGATAATGTGATAAAAGCTAAGGATTTGTATCAAACCTTTGGACGTCAATACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTATTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Peptidase S24-like (Peptidase_S24)

(184-296)

Helix-turn-helix (HTH_3)

(22-70)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A090B2L0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

100

100

1