Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   K6J59_RS03035 Genome accession   NZ_AP018782
Coordinates   617562..618068 (+) Length   168 a.a.
NCBI ID   WP_005649305.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-V-2 isolate 13H37     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 612562..623068
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J59_RS03015 (CHBNV2_05650) - 612671..613000 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  K6J59_RS03020 (CHBNV2_05660) - 613153..613998 (-) 846 WP_005666516.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  K6J59_RS03025 (CHBNV2_05670) - 614071..616665 (-) 2595 WP_005649307.1 penicillin-binding protein 1A -
  K6J59_RS03030 (CHBNV2_05680) comA 616764..617561 (+) 798 WP_005649306.1 pilus assembly protein PilM Machinery gene
  K6J59_RS03035 (CHBNV2_05690) comB 617562..618068 (+) 507 WP_005649305.1 competence protein ComB Machinery gene
  K6J59_RS03040 (CHBNV2_05700) comC 618065..618586 (+) 522 WP_005649304.1 competence protein ComC Machinery gene
  K6J59_RS03045 (CHBNV2_05710) comD 618583..618996 (+) 414 WP_005649303.1 pilus assembly protein PilP Machinery gene
  K6J59_RS03050 (CHBNV2_05720) comE 619006..620343 (+) 1338 WP_005649302.1 type IV pilus secretin PilQ family protein Machinery gene
  K6J59_RS03055 (CHBNV2_05730) - 620356..621042 (+) 687 WP_005649301.1 ComF family protein -
  K6J59_RS03060 (CHBNV2_05740) nfuA 621118..621714 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  K6J59_RS03065 (CHBNV2_05750) nudC 621781..622575 (+) 795 WP_005666520.1 NAD(+) diphosphatase -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19724.61 Da        Isoelectric Point: 8.5473

>NTDB_id=71350 K6J59_RS03035 WP_005649305.1 617562..618068(+) (comB) [Haemophilus influenzae strain CHBN-V-2 isolate 13H37]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQKSFEQLNQQLHKTTMQIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=71350 K6J59_RS03035 WP_005649305.1 617562..618068(+) (comB) [Haemophilus influenzae strain CHBN-V-2 isolate 13H37]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAGGCACAGCAAA
AGTCGTTTGAACAACTTAATCAACAGCTTCATAAAACTACCATGCAAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCGAATAACTTAAGTTTGGAAGGTAACGCGCAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

99.405

100

0.994
  comB Haemophilus influenzae Rd KW20

99.405

100

0.994

Multiple sequence alignment