Detailed information NTG0713332

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: NP435_RS13725
• Genome accession: NZ_CP101937
• Coordinates: 2616736..2619066 (-)
• Length: 776 a.a.
• NCBI ID: WP_009967776.1
• Uniprot ID: A0AAE2SL11
• Organism: Bacillus subtilis strain RUB331
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2611736..2624066

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NP435_RS13690 (NP435_13690)	yqxA	2612075..2612413 (-)	339	WP_004399162.1	YqxA family protein	-
NP435_RS13695 (NP435_13695)	spoIIP	2612430..2613635 (-)	1206	WP_003229993.1	spore autolysin SpoIIP	-
NP435_RS13700 (NP435_13700)	gpr	2613698..2614804 (-)	1107	WP_003229991.1	GPR endopeptidase	-
NP435_RS13705 (NP435_13705)	rpsT	2615008..2615274 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
NP435_RS13710 (NP435_13710)	holA	2615289..2616332 (-)	1044	WP_003229987.1	DNA polymerase III subunit delta	-
NP435_RS13715 (NP435_13715)	-	2616372..2616521 (-)	150	WP_003229985.1	hypothetical protein	-
NP435_RS13720 (NP435_13720)	yqzM	2616562..2616696 (+)	135	WP_003229983.1	YqzM family protein	-
NP435_RS13725 (NP435_13725)	comEC	2616736..2619066 (-)	2331	WP_009967776.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NP435_RS13730 (NP435_13730)	comEB	2619070..2619639 (-)	570	WP_003229978.1	ComE operon protein 2	-
NP435_RS13735 (NP435_13735)	comEA	2619706..2620323 (-)	618	WP_004398514.1	competence protein ComEA	Machinery gene
NP435_RS13740 (NP435_13740)	comER	2620407..2621228 (+)	822	WP_004398597.1	late competence protein ComER	-
NP435_RS13745 (NP435_13745)	yqeM	2621294..2622037 (-)	744	WP_003229973.1	class I SAM-dependent methyltransferase	-
NP435_RS13750 (NP435_13750)	rsfS	2622034..2622390 (-)	357	WP_003229971.1	ribosome silencing factor	-
NP435_RS13755 (NP435_13755)	yqeK	2622408..2622968 (-)	561	WP_004399059.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
NP435_RS13760 (NP435_13760)	nadD	2622958..2623527 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
NP435_RS13765 (NP435_13765)	yhbY	2623539..2623829 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86701.36 Da
• Isoelectric Point: 7.3497

>NTDB_id=713332 NP435_RS13725 WP_009967776.1 2616736..2619066(-) (comEC) [Bacillus subtilis strain RUB331]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVETPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSTGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVRSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWINRLITNIADVDVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAEILLKHHKVKRLVIPKGFVSEPKDEKVLQAAREEGVAIEEVKRGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMNVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQKVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=713332 NP435_RS13725 WP_009967776.1 2616736..2619066(-) (comEC) [Bacillus subtilis strain RUB331]
ATGCGTAATTCGCGCTTATTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTGAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTCAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTCTGCCTCCTGATTCGACAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTACGTGGAGGATGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATCCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGTCTTGTCAAATGGCGTGTCCGCTCTGCAACTGCAATTTGCCTTTCGTACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTCCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GATCAATAGGTTAATCACAAACATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACAGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGAGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAGCAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGATTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGGCAGCCAGGGAAG
AGGGAGTGGCAATTGAAGAGGTGAAGCGAGGCGATGTGTTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCGGAA
GCACCTGATCCGGCAAGCAAAAATAATTCATCTCTCGTTCTGTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAAGAGGTGATGAACGTGTTTCCGAATATAAAAGCAGATGTGTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAAAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	100	100	1