Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NP435_RS06235 Genome accession   NZ_CP101937
Coordinates   1208044..1208700 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis strain RUB331     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1203044..1213700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NP435_RS06205 (NP435_06205) oppF 1203509..1204426 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  NP435_RS06210 (NP435_06210) yjbB 1204533..1205750 (+) 1218 WP_010886478.1 MFS transporter -
  NP435_RS06215 (NP435_06215) yjbC 1205914..1206492 (+) 579 WP_003244921.1 GNAT family N-acetyltransferase -
  NP435_RS06220 (NP435_06220) spx 1206673..1207068 (+) 396 WP_003245483.1 transcriptional regulator Spx -
  NP435_RS06225 (NP435_06225) yjbE 1207111..1207767 (-) 657 WP_003232944.1 TerC family protein -
  NP435_RS06230 (NP435_06230) - 1207937..1208077 (+) 141 WP_119122854.1 hypothetical protein -
  NP435_RS06235 (NP435_06235) mecA 1208044..1208700 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  NP435_RS06240 (NP435_06240) - 1208695..1208817 (-) 123 WP_003245684.1 hypothetical protein -
  NP435_RS06245 (NP435_06245) coiA 1208861..1210012 (+) 1152 WP_003245839.1 competence protein CoiA Machinery gene
  NP435_RS06250 (NP435_06250) pepF 1210242..1212071 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  NP435_RS06255 (NP435_06255) - 1212109..1212276 (-) 168 WP_003244944.1 hypothetical protein -
  NP435_RS06260 (NP435_06260) spxH 1212590..1213489 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=713307 NP435_RS06235 WP_003245194.1 1208044..1208700(+) (mecA) [Bacillus subtilis strain RUB331]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=713307 NP435_RS06235 WP_003245194.1 1208044..1208700(+) (mecA) [Bacillus subtilis strain RUB331]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1