Detailed information
Bioinformatically predicted
Overview
| Name | nucA/comI | Type | Machinery gene |
| Locus tag | NP436_RS13260 | Genome accession | NZ_CP101932 |
| Coordinates | 2458613..2459023 (-) | Length | 136 a.a. |
| NCBI ID | WP_009967785.1 | Uniprot ID | A0A6I4D881 |
| Organism | Bacillus subtilis subsp. natto strain BGSC 27E1 | ||
| Function | cleavage of dsDNA into ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 2451717..2490145 | 2458613..2459023 | within | 0 |
Gene organization within MGE regions
Location: 2451717..2490145
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NP436_RS13220 (NP436_13220) | yqeH | 2451717..2452817 (-) | 1101 | WP_003229966.1 | ribosome biogenesis GTPase YqeH | - |
| NP436_RS13225 (NP436_13225) | yqeG | 2452821..2453339 (-) | 519 | WP_003226126.1 | YqeG family HAD IIIA-type phosphatase | - |
| NP436_RS13230 (NP436_13230) | - | 2453701..2453841 (+) | 141 | WP_003226124.1 | sporulation histidine kinase inhibitor Sda | - |
| NP436_RS13235 (NP436_13235) | yqeF | 2454147..2454878 (-) | 732 | WP_003229964.1 | SGNH/GDSL hydrolase family protein | - |
| NP436_RS13240 (NP436_13240) | cwlH | 2455130..2455882 (-) | 753 | WP_014480318.1 | N-acetylmuramoyl-L-alanine amidase CwlH | - |
| NP436_RS13245 (NP436_13245) | yqeD | 2456069..2456695 (+) | 627 | WP_014480319.1 | TVP38/TMEM64 family protein | - |
| NP436_RS13250 (NP436_13250) | gnd | 2456714..2457607 (-) | 894 | WP_014480320.1 | phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating) | - |
| NP436_RS13255 (NP436_13255) | yqeB | 2457858..2458580 (+) | 723 | WP_014480321.1 | hypothetical protein | - |
| NP436_RS13260 (NP436_13260) | nucA/comI | 2458613..2459023 (-) | 411 | WP_009967785.1 | sporulation-specific Dnase NucB | Machinery gene |
| NP436_RS13265 (NP436_13265) | sigK | 2459219..2459947 (+) | 729 | WP_013308023.1 | RNA polymerase sporulation sigma factor SigK | - |
| NP436_RS13270 (NP436_13270) | - | 2459947..2460045 (+) | 99 | WP_031600702.1 | hypothetical protein | - |
| NP436_RS13275 (NP436_13275) | - | 2460042..2460254 (-) | 213 | Protein_2567 | recombinase family protein | - |
| NP436_RS13280 (NP436_13280) | fumC | 2460473..2461861 (-) | 1389 | WP_014480325.1 | class II fumarate hydratase | - |
| NP436_RS13285 (NP436_13285) | - | 2462028..2462918 (+) | 891 | WP_014480326.1 | LysR family transcriptional regulator | - |
| NP436_RS13290 (NP436_13290) | - | 2463860..2464255 (+) | 396 | WP_014480327.1 | VOC family protein | - |
| NP436_RS13300 (NP436_13300) | - | 2464995..2466122 (-) | 1128 | WP_014480328.1 | Rap family tetratricopeptide repeat protein | - |
| NP436_RS22110 (NP436_13305) | - | 2466304..2467137 (+) | 834 | Protein_2572 | ribonuclease YeeF family protein | - |
| NP436_RS22115 (NP436_13310) | - | 2467523..2468230 (+) | 708 | WP_014480330.1 | hypothetical protein | - |
| NP436_RS13315 (NP436_13315) | - | 2468244..2468531 (+) | 288 | WP_014480331.1 | hypothetical protein | - |
| NP436_RS13320 (NP436_13320) | - | 2468934..2469374 (+) | 441 | WP_014480332.1 | SMI1/KNR4 family protein | - |
| NP436_RS13325 (NP436_13325) | - | 2469473..2469925 (+) | 453 | WP_014480333.1 | SMI1/KNR4 family protein | - |
| NP436_RS13330 (NP436_13330) | cdiI | 2470022..2470381 (+) | 360 | WP_014480334.1 | ribonuclease toxin immunity protein CdiI | - |
| NP436_RS13335 (NP436_13335) | - | 2470486..2470965 (+) | 480 | WP_224588637.1 | hypothetical protein | - |
| NP436_RS13340 (NP436_13340) | - | 2471121..2472368 (+) | 1248 | WP_031600262.1 | IS256-like element ISBsu2 family transposase | - |
| NP436_RS13345 (NP436_13345) | - | 2472650..2472853 (-) | 204 | WP_123772462.1 | hypothetical protein | - |
| NP436_RS13350 (NP436_13350) | - | 2472942..2473175 (+) | 234 | WP_224588641.1 | hypothetical protein | - |
| NP436_RS13355 (NP436_13355) | atxG | 2473443..2474020 (+) | 578 | Protein_2582 | suppressor of fused domain protein | - |
| NP436_RS13360 (NP436_13360) | - | 2474130..2474420 (+) | 291 | WP_014480337.1 | contact-dependent growth inhibition system immunity protein | - |
| NP436_RS13365 (NP436_13365) | istA | 2475261..2476808 (+) | 1548 | WP_014480339.1 | IS21 family transposase | - |
| NP436_RS13370 (NP436_13370) | istB | 2476805..2477563 (+) | 759 | WP_014479891.1 | IS21-like element helper ATPase IstB | - |
| NP436_RS22120 | - | 2477815..2477981 (-) | 167 | Protein_2586 | peptidoglycan-binding protein | - |
| NP436_RS13380 (NP436_13380) | - | 2478156..2478242 (+) | 87 | WP_072592549.1 | putative holin-like toxin | - |
| NP436_RS22125 | - | 2478529..2479004 (-) | 476 | Protein_2588 | phage tail tube protein | - |
| NP436_RS13395 (NP436_13395) | terS | 2478964..2479528 (-) | 565 | Protein_2589 | phage terminase small subunit | - |
| NP436_RS13400 (NP436_13400) | - | 2479655..2479960 (+) | 306 | WP_123772463.1 | hypothetical protein | - |
| NP436_RS13410 (NP436_13410) | - | 2480353..2480832 (-) | 480 | WP_014480344.1 | hypothetical protein | - |
| NP436_RS13415 (NP436_13415) | - | 2481449..2481715 (+) | 267 | WP_033881358.1 | hypothetical protein | - |
| NP436_RS13420 (NP436_13420) | - | 2481854..2482006 (-) | 153 | WP_049832653.1 | XtrA/YqaO family protein | - |
| NP436_RS13425 (NP436_13425) | - | 2482089..2482211 (-) | 123 | Protein_2594 | RusA family crossover junction endodeoxyribonuclease | - |
| NP436_RS13430 (NP436_13430) | - | 2482174..2482422 (-) | 249 | Protein_2595 | hypothetical protein | - |
| NP436_RS13435 (NP436_13435) | - | 2482567..2482797 (-) | 231 | WP_224588644.1 | hypothetical protein | - |
| NP436_RS13440 (NP436_13440) | - | 2483106..2483286 (-) | 181 | Protein_2597 | hypothetical protein | - |
| NP436_RS13445 (NP436_13445) | bltR | 2483494..2484315 (-) | 822 | WP_014480349.1 | multidrug efflux transcriptional regulator BltR | - |
| NP436_RS13450 (NP436_13450) | blt | 2484432..2485634 (+) | 1203 | WP_014480350.1 | multidrug efflux MFS transporter Blt | - |
| NP436_RS13455 (NP436_13455) | bltD | 2485816..2486274 (+) | 459 | WP_014480351.1 | spermine/spermidine acetyltransferase | - |
| NP436_RS13460 (NP436_13460) | yrkA | 2486433..2487737 (-) | 1305 | WP_014480352.1 | hemolysin family protein | - |
| NP436_RS13465 (NP436_13465) | yrzO | 2488027..2488170 (-) | 144 | WP_014477437.1 | YrzO family protein | - |
| NP436_RS13470 (NP436_13470) | yrdR | 2488188..2489153 (-) | 966 | WP_014480354.1 | DMT family transporter | - |
| NP436_RS13475 (NP436_13475) | czcR | 2489279..2490145 (+) | 867 | WP_014480355.1 | LysR family transcriptional regulator CzcR | - |
Sequence
Protein
Download Length: 136 a.a. Molecular weight: 14967.97 Da Isoelectric Point: 5.1853
>NTDB_id=713173 NP436_RS13260 WP_009967785.1 2458613..2459023(-) (nucA/comI) [Bacillus subtilis subsp. natto strain BGSC 27E1]
MKKWMAGLFLAAAVLLCLMVPQQIQGASSYDKVLYFPLSRYPETGSHIRDAIAEGHPDICTIDRDGADKRREESLKGIPT
KPGYDRDEWPMAVCEEGGAGADVRYVTPSDNRGAGSWVGNQMSSYPDGTRVLFIVQ
MKKWMAGLFLAAAVLLCLMVPQQIQGASSYDKVLYFPLSRYPETGSHIRDAIAEGHPDICTIDRDGADKRREESLKGIPT
KPGYDRDEWPMAVCEEGGAGADVRYVTPSDNRGAGSWVGNQMSSYPDGTRVLFIVQ
Nucleotide
Download Length: 411 bp
>NTDB_id=713173 NP436_RS13260 WP_009967785.1 2458613..2459023(-) (nucA/comI) [Bacillus subtilis subsp. natto strain BGSC 27E1]
ATGAAAAAATGGATGGCAGGCCTGTTTCTTGCTGCAGCAGTTCTTCTTTGTTTAATGGTTCCGCAACAGATCCAAGGCGC
ATCTTCGTATGACAAAGTGTTATATTTTCCGCTGTCTCGTTATCCGGAAACCGGCAGTCATATTAGAGATGCGATTGCAG
AGGGACATCCAGATATTTGTACCATTGACAGAGATGGAGCAGACAAAAGGCGGGAGGAATCTTTAAAGGGAATCCCGACC
AAGCCGGGCTATGACCGGGATGAGTGGCCGATGGCGGTCTGCGAGGAAGGCGGCGCAGGGGCTGATGTCCGATATGTGAC
GCCTTCTGATAATCGCGGCGCCGGCTCGTGGGTAGGGAATCAAATGAGCAGCTATCCTGACGGCACCAGAGTGCTGTTTA
TTGTGCAGTAG
ATGAAAAAATGGATGGCAGGCCTGTTTCTTGCTGCAGCAGTTCTTCTTTGTTTAATGGTTCCGCAACAGATCCAAGGCGC
ATCTTCGTATGACAAAGTGTTATATTTTCCGCTGTCTCGTTATCCGGAAACCGGCAGTCATATTAGAGATGCGATTGCAG
AGGGACATCCAGATATTTGTACCATTGACAGAGATGGAGCAGACAAAAGGCGGGAGGAATCTTTAAAGGGAATCCCGACC
AAGCCGGGCTATGACCGGGATGAGTGGCCGATGGCGGTCTGCGAGGAAGGCGGCGCAGGGGCTGATGTCCGATATGTGAC
GCCTTCTGATAATCGCGGCGCCGGCTCGTGGGTAGGGAATCAAATGAGCAGCTATCCTGACGGCACCAGAGTGCTGTTTA
TTGTGCAGTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| nucA/comI | Bacillus subtilis subsp. subtilis str. 168 |
62.609 |
84.559 |
0.529 |