Detailed information NTG0713014

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: NP433_RS12760
• Genome accession: NZ_CP101930
• Coordinates: 2504392..2506722 (-)
• Length: 776 a.a.
• NCBI ID: WP_256682881.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain BGSC 10A5
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2499392..2511722

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NP433_RS12725 (NP433_12725)	yqxA	2499731..2500069 (-)	339	WP_033884453.1	YqxA family protein	-
NP433_RS12730 (NP433_12730)	spoIIP	2500086..2501291 (-)	1206	WP_088326541.1	spore autolysin SpoIIP	-
NP433_RS12735 (NP433_12735)	gpr	2501354..2502460 (-)	1107	WP_109962781.1	GPR endopeptidase	-
NP433_RS12740 (NP433_12740)	rpsT	2502664..2502930 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
NP433_RS12745 (NP433_12745)	holA	2502945..2503988 (-)	1044	WP_029317888.1	DNA polymerase III subunit delta	-
NP433_RS12750 (NP433_12750)	-	2504028..2504177 (-)	150	WP_003229985.1	hypothetical protein	-
NP433_RS12755 (NP433_12755)	yqzM	2504218..2504352 (+)	135	WP_003229983.1	YqzM family protein	-
NP433_RS12760 (NP433_12760)	comEC	2504392..2506722 (-)	2331	WP_256682881.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NP433_RS12765 (NP433_12765)	comEB	2506726..2507295 (-)	570	WP_003229978.1	ComE operon protein 2	-
NP433_RS12770 (NP433_12770)	comEA	2507362..2507979 (-)	618	WP_029317886.1	competence protein ComEA	Machinery gene
NP433_RS12775 (NP433_12775)	comER	2508063..2508884 (+)	822	WP_014480313.1	late competence protein ComER	-
NP433_RS12780 (NP433_12780)	yqeM	2508950..2509693 (-)	744	WP_029317885.1	class I SAM-dependent methyltransferase	-
NP433_RS12785 (NP433_12785)	rsfS	2509690..2510046 (-)	357	WP_041333759.1	ribosome silencing factor	-
NP433_RS12790 (NP433_12790)	yqeK	2510064..2510624 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
NP433_RS12795 (NP433_12795)	nadD	2510614..2511183 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
NP433_RS12800 (NP433_12800)	yhbY	2511195..2511485 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86765.36 Da
• Isoelectric Point: 7.1434

>NTDB_id=713014 NP433_RS12760 WP_256682881.1 2504392..2506722(-) (comEC) [Bacillus subtilis strain BGSC 10A5]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVETPDKEKWAAAYRIQSAGEKEQLLYIEPGVSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVDVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMITGG
ICCTVLFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAEILLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPE
TPDPSSKNNSSLVLWMEMGVLSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQKVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=713014 NP433_RS12760 WP_256682881.1 2504392..2506722(-) (comEC) [Bacillus subtilis strain BGSC 10A5]
ATGCGTAATTCGCGCTTATTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTCATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACTTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTGAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAGTGTCATGTGAGTTAA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATTCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTTTGCCTCCTGATTCGGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAGGATGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATTCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGACAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTTCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGTTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGATAACCGGCGGC
ATTTGCTGCACGGTGCTGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGATTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
ACACCTGATCCGTCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGATGGGCGTTCTGAGCTGGATTTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAAAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	98.196	100	0.982