Detailed information NTG0712610

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: NPS25_RS17465
• Genome accession: NZ_CP101904
• Coordinates: 3566649..3567812 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain Ba-0321
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3561649..3572812

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NPS25_RS17435 (NPS25_17435)	-	3561914..3562333 (-)	420	WP_015418333.1	TIGR03826 family flagellar region protein	-
NPS25_RS17440 (NPS25_17440)	comFC	3562407..3563096 (-)	690	WP_196493397.1	phosphoribosyltransferase family protein	Machinery gene
NPS25_RS17445 (NPS25_17445)	-	3563102..3563386 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
NPS25_RS17450 (NPS25_17450)	comFA	3563444..3564829 (-)	1386	WP_015418335.1	DEAD/DEAH box helicase	Machinery gene
NPS25_RS17455 (NPS25_17455)	-	3564937..3565785 (-)	849	WP_015418336.1	DegV family protein	-
NPS25_RS17460 (NPS25_17460)	degU	3565883..3566572 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
NPS25_RS17465 (NPS25_17465)	degS	3566649..3567812 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
NPS25_RS17470 (NPS25_17470)	-	3568035..3568682 (+)	648	WP_003151384.1	YigZ family protein	-
NPS25_RS17475 (NPS25_17475)	-	3568687..3569901 (+)	1215	WP_033575220.1	LCP family protein	-
NPS25_RS17480 (NPS25_17480)	-	3569991..3571067 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
NPS25_RS17485 (NPS25_17485)	-	3571200..3572396 (-)	1197	WP_015418338.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=712610 NPS25_RS17465 WP_007407484.1 3566649..3567812(-) (degS) [Bacillus velezensis strain Ba-0321]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=712610 NPS25_RS17465 WP_007407484.1 3566649..3567812(-) (degS) [Bacillus velezensis strain Ba-0321]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951