Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NPS25_RS05915 Genome accession   NZ_CP101904
Coordinates   1171326..1171982 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain Ba-0321     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1166326..1176982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS25_RS05890 (NPS25_05890) oppF 1166856..1167773 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  NPS25_RS05895 (NPS25_05895) - 1167880..1169067 (+) 1188 WP_076982893.1 putative glycoside hydrolase -
  NPS25_RS05900 (NPS25_05900) - 1169185..1169763 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  NPS25_RS05905 (NPS25_05905) spx 1169941..1170336 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  NPS25_RS05910 (NPS25_05910) - 1170394..1171050 (-) 657 WP_007409109.1 TerC family protein -
  NPS25_RS05915 (NPS25_05915) mecA 1171326..1171982 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  NPS25_RS05920 (NPS25_05920) - 1172133..1173293 (+) 1161 WP_060675051.1 competence protein CoiA family protein -
  NPS25_RS05925 (NPS25_05925) pepF 1173521..1175350 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  NPS25_RS05930 (NPS25_05930) - 1175388..1175555 (-) 168 WP_003155026.1 hypothetical protein -
  NPS25_RS05935 (NPS25_05935) spxH 1175841..1176743 (-) 903 WP_039251990.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=712567 NPS25_RS05915 WP_003155032.1 1171326..1171982(+) (mecA) [Bacillus velezensis strain Ba-0321]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=712567 NPS25_RS05915 WP_003155032.1 1171326..1171982(+) (mecA) [Bacillus velezensis strain Ba-0321]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895