Detailed information NTG0712319

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: NOV99_RS07555
• Genome accession: NZ_CP101844
• Coordinates: 1517591..1520044 (-)
• Length: 817 a.a.
• NCBI ID: WP_240020715.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 2018WUSS151
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1512591..1525044

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NOV99_RS07525 (NOV99_07525)	hslO	1513931..1514797 (+)	867	WP_002937786.1	Hsp33 family molecular chaperone HslO	-
NOV99_RS07530 (NOV99_07530)	dusB	1514790..1515794 (+)	1005	WP_002937787.1	tRNA dihydrouridine synthase DusB	-
NOV99_RS07535 (NOV99_07535)	-	1515908..1516150 (-)	243	WP_002937789.1	hypothetical protein	-
NOV99_RS07540 (NOV99_07540)	-	1516147..1516380 (-)	234	WP_002937793.1	hypothetical protein	-
NOV99_RS07545 (NOV99_07545)	-	1516400..1516783 (-)	384	WP_002937798.1	hypothetical protein	-
NOV99_RS07550 (NOV99_07550)	-	1516981..1517472 (-)	492	WP_002937801.1	adenylyltransferase/cytidyltransferase family protein	-
NOV99_RS07555 (NOV99_07555)	clpC	1517591..1520044 (-)	2454	WP_240020715.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NOV99_RS07560 (NOV99_07560)	-	1520048..1520506 (-)	459	WP_002937810.1	CtsR family transcriptional regulator	-
NOV99_RS07565 (NOV99_07565)	-	1520776..1521114 (+)	339	WP_002937812.1	thioredoxin domain-containing protein	-
NOV99_RS07570 (NOV99_07570)	-	1521114..1521815 (+)	702	WP_002937813.1	hypothetical protein	-
NOV99_RS07575 (NOV99_07575)	tsf	1521971..1523011 (-)	1041	WP_002937816.1	translation elongation factor Ts	-
NOV99_RS07580 (NOV99_07580)	rpsB	1523320..1524096 (-)	777	WP_014637198.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90352.85 Da
• Isoelectric Point: 6.0792

>NTDB_id=712319 NOV99_RS07555 WP_240020715.1 1517591..1520044(-) (clpC) [Streptococcus suis strain 2018WUSS151]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFIVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFCFEDSDDKFRFLDLRKNVEARAGFTKEDLK
AIRSVMKGGKAKPANMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILARKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTESDMQDVVKVMVKPLFAVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLATGST
LKVGVKGEELKFDVVKG

Nucleotide

• Length: 2454 bp

>NTDB_id=712319 NOV99_RS07555 WP_240020715.1 1517591..1520044(-) (clpC) [Streptococcus suis strain 2018WUSS151]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGCTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCTGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTATTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACGGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTGTTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACGTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTGCCAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTAGCACGTAAAACCAAGAACAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ATGACATCGAGGAAGATGGTCAGGTCATCCTTTTCATCGATGAGTTGCATACCATTATGGGTTCTGGCTCGGGGATTGAT
TCAACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACGACTCAGAC
AGAGTACCAAAAGCATATTGAGAAAGACGCAGCCCTGGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTTG
AGGACAGTATTGCCATTTTGACAGGGCTTAAAGGTACTTTTGAGAAATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTACCGGATTCAGCCATTGATCTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGCATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCAGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGTAAG
ACAGAGCTTGCTAAAGCCTTGGCAGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATAT
GGAGAAATTTGCGGCCAGCCGTCTCAATGGAGCGCCTCCAGGCTACGTGGGCTATGAAGAAGGTGGCGAATTGACAGAAA
AAGTTCGTAACAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGATGGTGTCTTGACGGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACCATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTGTCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAGGCCTACCGTCCTGAATTTATCAACCGTATTGATGAAAAAGTTGTCTTC
CATAGTTTGACCGAATCCGATATGCAGGATGTTGTCAAGGTCATGGTCAAACCGTTGTTTGCGGTAACAGCTGAGAAAGG
AATTACTCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAACAAGGTTACGACCCAGAAATGGGGGCTCGTCCTC
TTCGTAGACTCTTACAAACCAAATTGGAAGATCCGTTGGCAGAAATGTTGCTCCGTGGTGACTTGGCTACTGGTTCGACC
CTGAAGGTTGGGGTCAAGGGTGAAGAGCTCAAGTTTGATGTGGTAAAGGGATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (372-457)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-129)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	71.656	99.755	0.715
clpC	Streptococcus pneumoniae D39	71.656	99.755	0.715
clpC	Streptococcus pneumoniae TIGR4	71.656	99.755	0.715
clpC	Streptococcus mutans UA159	66.953	99.633	0.667
clpC	Streptococcus thermophilus LMD-9	63.962	100	0.656
clpC	Streptococcus thermophilus LMG 18311	64.38	100	0.655
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.161	100	0.502
clpC	Bacillus subtilis subsp. subtilis str. 168	42.994	100	0.439