Detailed information NTG0712313

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NOV99_RS05070
• Genome accession: NZ_CP101844
• Coordinates: 1012490..1013539 (-)
• Length: 349 a.a.
• NCBI ID: WP_004194592.1
• Uniprot ID: A0A0N0DPM5
• Organism: Streptococcus suis strain 2018WUSS151
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1007490..1018539

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NOV99_RS05050 (NOV99_05050)	nadE	1008318..1009142 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
NOV99_RS05055 (NOV99_05055)	-	1010016..1010543 (-)	528	WP_004194600.1	VanZ family protein	-
NOV99_RS05060 (NOV99_05060)	rlmN	1010540..1011652 (-)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NOV99_RS05065 (NOV99_05065)	-	1011661..1012302 (-)	642	WP_004194595.1	YutD-like domain-containing protein	-
NOV99_RS05070 (NOV99_05070)	sepM	1012490..1013539 (-)	1050	WP_004194592.1	SepM family pheromone-processing serine protease	Regulator
NOV99_RS05075 (NOV99_05075)	coaD	1013526..1014014 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
NOV99_RS05080 (NOV99_05080)	rsmD	1014004..1014543 (-)	540	WP_024394248.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NOV99_RS05085 (NOV99_05085)	-	1014842..1015564 (-)	723	WP_013730502.1	hypothetical protein	-
NOV99_RS05090 (NOV99_05090)	-	1015621..1016007 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NOV99_RS05095 (NOV99_05095)	-	1016007..1016225 (-)	219	WP_004194736.1	YqgQ family protein	-
NOV99_RS05100 (NOV99_05100)	-	1016525..1017127 (-)	603	WP_004194738.1	response regulator transcription factor	-
NOV99_RS05105 (NOV99_05105)	-	1017124..1018218 (-)	1095	WP_240020680.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37747.80 Da
• Isoelectric Point: 4.6112

>NTDB_id=712313 NOV99_RS05070 WP_004194592.1 1012490..1013539(-) (sepM) [Streptococcus suis strain 2018WUSS151]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=712313 NOV99_RS05070 WP_004194592.1 1012490..1013539(-) (sepM) [Streptococcus suis strain 2018WUSS151]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0N0DPM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605