Detailed information NTG0071150

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: K6J67_RS03605
• Genome accession: NZ_AP018776
• Coordinates: 709258..710478 (+)
• Length: 406 a.a.
• NCBI ID: WP_042601844.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain CHBN-III-5 isolate 13H30
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 704258..715478

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6J67_RS03585 (CHBNIII5_06900)	corC	705221..706120 (-)	900	WP_011961742.1	CNNM family magnesium/cobalt transport protein CorC	-
K6J67_RS03590 (CHBNIII5_06910)	ampD	706743..707303 (-)	561	WP_005648974.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
K6J67_RS03595 (CHBNIII5_06920)	pilA	707418..707867 (+)	450	WP_042601842.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
K6J67_RS03600 (CHBNIII5_06930)	pilB	707864..709261 (+)	1398	WP_042601843.1	GspE/PulE family protein	Machinery gene
K6J67_RS03605 (CHBNIII5_06940)	pilC	709258..710478 (+)	1221	WP_042601844.1	type II secretion system F family protein	Machinery gene
K6J67_RS03610 (CHBNIII5_06950)	pilD	710475..711167 (+)	693	WP_050822711.1	A24 family peptidase	Machinery gene
K6J67_RS03615 (CHBNIII5_06960)	rho	711221..712483 (-)	1263	WP_005666690.1	transcription termination factor Rho	-
K6J67_RS03620 (CHBNIII5_06970)	metJ	712731..713048 (+)	318	WP_005631186.1	met regulon transcriptional regulator MetJ	-
K6J67_RS03625 (CHBNIII5_06980)	cueR	713062..713448 (-)	387	WP_005648963.1	Cu(I)-responsive transcriptional regulator	-
K6J67_RS03630 (CHBNIII5_06990)	-	713525..713731 (+)	207	WP_005631184.1	heavy-metal-associated domain-containing protein	-
K6J67_RS03635 (CHBNIII5_07000)	-	713805..714011 (+)	207	WP_012054944.1	heavy-metal-associated domain-containing protein	-
K6J67_RS03640 (CHBNIII5_07010)	-	714097..714303 (+)	207	WP_012054944.1	heavy-metal-associated domain-containing protein	-
K6J67_RS03645 (CHBNIII5_07020)	-	714389..714595 (+)	207	WP_005631184.1	heavy-metal-associated domain-containing protein	-

Sequence

Protein

• Length: 406 a.a.
• Molecular weight: 46205.41 Da
• Isoelectric Point: 9.7152

>NTDB_id=71150 K6J67_RS03605 WP_042601844.1 709258..710478(+) (pilC) [Haemophilus influenzae strain CHBN-III-5 isolate 13H30]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQDCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide

• Length: 1221 bp

>NTDB_id=71150 K6J67_RS03605 WP_042601844.1 709258..710478(+) (pilC) [Haemophilus influenzae strain CHBN-III-5 isolate 13H30]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAGATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (266-397)

• Type II secretion system (T2SS), protein F (T2SSF) (63-185)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Haemophilus influenzae 86-028NP	98.03	100	0.98
pilC	Haemophilus influenzae Rd KW20	97.291	100	0.973
pilC	Glaesserella parasuis strain SC1401	38.404	98.768	0.379