Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   POF63_RS06290 Genome accession   NZ_CP116708
Coordinates   1206231..1206713 (-) Length   160 a.a.
NCBI ID   WP_000163512.1    Uniprot ID   Q8DZB3
Organism   Streptococcus agalactiae strain CNCTC 10/84 sCas9     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1201231..1211713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  POF63_RS06270 (POF63_06270) alsS 1201490..1203172 (-) 1683 WP_000140344.1 acetolactate synthase AlsS -
  POF63_RS06275 (POF63_06275) - 1203282..1204508 (-) 1227 WP_000934874.1 hypothetical protein -
  POF63_RS06280 (POF63_06280) - 1204498..1205688 (-) 1191 WP_001081537.1 AI-2E family transporter -
  POF63_RS06285 (POF63_06285) - 1205780..1206241 (-) 462 WP_000796049.1 NUDIX hydrolase -
  POF63_RS06290 (POF63_06290) mutX 1206231..1206713 (-) 483 WP_000163512.1 8-oxo-dGTP diphosphatase Machinery gene
  POF63_RS06295 (POF63_06295) hylB 1206931..1210150 (+) 3220 Protein_1161 hyaluronate lyase -
  POF63_RS06300 (POF63_06300) rfbB 1210202..1211248 (-) 1047 WP_000134279.1 dTDP-glucose 4,6-dehydratase -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 18837.23 Da        Isoelectric Point: 4.5116

>NTDB_id=711266 POF63_RS06290 WP_000163512.1 1206231..1206713(-) (mutX) [Streptococcus agalactiae strain CNCTC 10/84 sCas9]
MTKLATICYIDNGKELLLLHRNKKENDVHEGKWISVGGKLEAGETPDECAKREILEETHLTVKKMDFKGVITFPEFTPGH
DWYTYVFKVTDYEGELISDDESREGTLEWVPYDQVLSKPTWQGDYEIFKWILEDVPFFSAKFVYDEHQNLIEKTVNFYEK

Nucleotide


Download         Length: 483 bp        

>NTDB_id=711266 POF63_RS06290 WP_000163512.1 1206231..1206713(-) (mutX) [Streptococcus agalactiae strain CNCTC 10/84 sCas9]
ATGACTAAATTAGCAACAATTTGTTACATTGACAATGGCAAGGAATTACTTCTATTGCACCGCAACAAAAAAGAGAATGA
TGTTCATGAGGGAAAGTGGATCTCGGTAGGTGGTAAACTGGAGGCAGGTGAAACTCCTGATGAATGTGCTAAGCGTGAAA
TTCTAGAAGAAACCCATTTAACGGTAAAAAAAATGGATTTTAAAGGAGTCATCACTTTTCCTGAATTTACGCCAGGTCAT
GATTGGTATACCTATGTCTTTAAAGTAACAGATTATGAAGGAGAGTTAATTTCAGATGATGAATCACGAGAAGGAACTTT
AGAATGGGTACCATATGATCAAGTTCTTTCTAAGCCAACGTGGCAAGGAGATTACGAAATTTTTAAATGGATTTTAGAAG
ATGTTCCTTTCTTTTCTGCTAAGTTTGTTTATGATGAACACCAAAATTTAATTGAAAAGACGGTTAATTTTTATGAAAAA
TAG

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(3-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DZB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

71.698

99.375

0.712