Detailed information NTG0711256

Bioinformatically predicted

Overview

• Name: rexA
• Type: Machinery gene
• Locus tag: POF63_RS04740
• Genome accession: NZ_CP116708
• Coordinates: 881236..884859 (+)
• Length: 1207 a.a.
• NCBI ID: WP_000143246.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain CNCTC 10/84 sCas9
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 876236..889859

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
POF63_RS04730 (POF63_04730)	-	876933..877835 (-)	903	WP_000686765.1	neutral zinc metallopeptidase	-
POF63_RS04735 (POF63_04735)	rexB	878013..881246 (+)	3234	WP_000772302.1	ATP-dependent nuclease subunit B	Machinery gene
POF63_RS04740 (POF63_04740)	rexA	881236..884859 (+)	3624	WP_000143246.1	helicase-exonuclease AddAB subunit AddA	Machinery gene
POF63_RS04745 (POF63_04745)	-	884872..885789 (+)	918	WP_000634649.1	magnesium transporter CorA family protein	-
POF63_RS04750 (POF63_04750)	mnmE	885821..887197 (-)	1377	WP_000028891.1	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	-
POF63_RS04755 (POF63_04755)	-	887502..887852 (+)	351	WP_000752065.1	hypothetical protein	-

Sequence

Protein

• Length: 1207 a.a.
• Molecular weight: 139488.91 Da
• Isoelectric Point: 5.3986

>NTDB_id=711256 POF63_RS04740 WP_000143246.1 881236..884859(+) (rexA) [Streptococcus agalactiae strain CNCTC 10/84 sCas9]
MTFKPFLNQEDIAVIQTEEKNSDKKQKRTSEQIEAIYTFGNNVLVSASAGSGKTFVMVERILDKLLRGVPIESLFISTFT
VKAAGELKERLEKKINESLKSAESDDLKQFLTQQLVGIQTADIGTMDAFTQKIVNQYGYTLGISPIFRILQDKNEQDVIK
NEVYADLFSDYMTGKNAASFIKLVKNFSGNRKDSKAFREMVYKVYAFSQSTDNPKRWMQTVFLKGAQTYTDFDAIPDQEV
SSLLNVMQTTANQLRDLTEQEDYKQLTAKGVPTANYKKHLKIIENLVHWSQDFNLLYGKKGLANLARDITNVIPSGNDVT
VAGLKYPIFKQLHNRIVGLKHLEIIFKYQGESLFLLELLQSFVLDFSEQYLQEKIQENAFEFSDIAHFAIQILEENHDIR
QLYQDKYHEVMVDEYQDNNHTQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNDKYKAYQDNPNQGKLIILKENFR
SQSEVLDSTNSVFTHLMDEEVGDILYDESHQLKAGSPRQQERHPNNKTQVLLLDTDEDDINDSDSQQYDISPAEAKLVAK
EIIRLHKEENVPFQDITLLVSSRTRNDGILQTFDRYGIPLVTDGGEQNYLKSVEVMVMLDTLRSIDNPLNDYALVALLRS
PMFGFNEDDLTRIAIQDVKMAFYHKVKLSYHKEGHHSDLIIPELSSKIDHFMKTFQTWRDFAKWHSLYDLIWKIYNDRFY
YDYVGALPKAEQRQANLYALALRANQFEKTGFKGLSRFIRMIDKVLENENDLADVEVALPQNAVNLMTIHKSKGLEFKYV
FILNIDKKFSMVDITSPLILSRNQGIGIKYVADMRHELEEEILPAVKVSMETLPYQLNKRELRLATLSEQMRLLYVAMTR
AEKKLYLVGKASQTKWADHYDLVSENNHLPLASRETFVTFQDWLLAVHETYKKQELFYDINFVSLEELTDHHIGMVNPSL
PFNPDNKAENRQSEDIVRAISVLESVEQINQTYKAAIELPTVRTPSQVKKFYEPILDIEGVDVMETITKTSVDFKLPDFS
TSKKQDPAALGSAVHELMQRIEMSSHVKMEDIQKALTEVNAETSVKAAIQIEKINYFFQETSLGKYIQEEVEHLHREAPF
AMLKEDPESGEKFVVRGIIDGYLLLENRIILFDYKTDKFVNPLELKERYQGQMALYAEALKKSYEIEKIDKYLILLGGKQ
LEVVKMD

Nucleotide

• Length: 3624 bp

>NTDB_id=711256 POF63_RS04740 WP_000143246.1 881236..884859(+) (rexA) [Streptococcus agalactiae strain CNCTC 10/84 sCas9]
ATGACCTTTAAGCCTTTCTTAAATCAAGAAGATATTGCTGTTATTCAGACAGAAGAAAAAAATTCTGATAAAAAACAAAA
GCGAACGTCTGAACAAATTGAAGCCATTTATACTTTTGGTAACAATGTCCTGGTATCAGCTTCGGCTGGTTCTGGAAAGA
CTTTTGTAATGGTTGAGCGGATTTTAGATAAACTTTTAAGAGGGGTTCCGATTGAGTCTTTGTTTATCTCAACATTTACA
GTAAAAGCGGCAGGTGAGCTCAAAGAACGTTTAGAAAAGAAAATAAACGAGTCTTTGAAATCCGCAGAATCAGATGATTT
AAAACAGTTTCTCACCCAGCAACTTGTCGGCATTCAAACAGCTGATATTGGTACTATGGATGCTTTTACGCAAAAAATAG
TTAACCAATATGGTTATACTTTGGGCATATCACCTATATTTAGGATTTTACAAGATAAAAATGAGCAAGACGTCATAAAG
AATGAGGTCTATGCTGATTTATTTTCTGACTACATGACTGGGAAGAATGCAGCTTCATTCATAAAATTAGTCAAAAATTT
CTCAGGTAACCGTAAAGATAGCAAAGCTTTTCGAGAAATGGTTTATAAAGTTTATGCTTTTAGCCAGTCCACCGATAATC
CCAAGCGCTGGATGCAAACAGTTTTTCTAAAAGGTGCACAAACTTACACTGATTTTGATGCTATTCCAGATCAAGAAGTT
TCAAGCCTTTTAAATGTAATGCAAACAACTGCTAATCAATTACGTGATTTAACGGAGCAAGAAGATTATAAGCAATTAAC
TGCTAAAGGGGTTCCGACAGCAAATTACAAAAAACACCTTAAAATAATTGAAAATTTAGTCCATTGGTCTCAAGACTTTA
ATCTGCTGTATGGAAAAAAAGGATTGGCTAATTTGGCACGTGATATCACTAATGTGATTCCTTCAGGCAATGATGTTACA
GTTGCTGGCCTTAAATATCCTATCTTTAAACAATTGCATAATCGTATCGTTGGACTTAAGCACTTAGAAATTATTTTTAA
GTATCAAGGGGAATCTCTTTTCTTGTTAGAATTATTGCAATCCTTTGTTTTAGATTTCTCAGAACAATATTTACAGGAGA
AGATTCAAGAAAATGCTTTTGAATTTTCTGATATTGCCCATTTTGCAATTCAAATATTGGAAGAAAATCATGATATTAGG
CAACTTTATCAAGATAAGTATCATGAAGTAATGGTTGATGAGTATCAGGACAATAATCACACCCAAGAGAGAATGTTAGA
ATTATTGTCTAATGGACATAATCGTTTCATGGTTGGAGACATAAAACAATCAATTTACCGTTTTCGTCAGGCTGATCCAC
AAATTTTTAATGATAAATACAAAGCTTACCAAGACAATCCTAATCAAGGGAAATTAATTATTCTGAAAGAGAATTTTCGG
AGTCAATCAGAGGTTTTAGACAGTACAAATAGTGTGTTTACACATCTTATGGATGAAGAAGTAGGAGACATTCTTTATGA
TGAAAGTCACCAATTAAAAGCTGGTAGTCCAAGACAGCAAGAAAGACATCCGAATAATAAAACACAAGTTTTACTATTAG
ATACTGATGAAGATGATATAAATGACAGTGATAGTCAACAATATGATATTAGCCCAGCTGAAGCAAAGTTAGTCGCAAAA
GAAATTATTCGATTGCATAAAGAAGAGAATGTTCCTTTTCAAGATATCACCCTCTTAGTTTCTTCAAGGACAAGGAATGA
TGGTATCTTACAAACTTTTGACCGTTATGGTATTCCTTTGGTAACTGACGGTGGGGAGCAAAATTACTTAAAATCAGTCG
AAGTGATGGTAATGCTTGATACTTTGCGGTCAATTGATAATCCCTTAAATGATTATGCTCTAGTTGCTCTTTTGAGATCT
CCCATGTTTGGCTTTAATGAAGATGATTTAACAAGAATTGCTATTCAGGATGTCAAAATGGCTTTTTATCATAAAGTGAA
ATTGTCTTATCATAAAGAAGGTCATCATAGTGATTTAATTATTCCAGAATTATCTTCTAAAATAGATCACTTTATGAAAA
CATTCCAGACTTGGCGTGATTTTGCTAAATGGCATTCGCTTTATGATTTAATATGGAAAATATATAATGACCGTTTTTAT
TATGATTATGTAGGAGCTCTGCCTAAAGCTGAGCAACGTCAAGCCAATCTATATGCCTTGGCACTTCGAGCAAATCAGTT
TGAAAAAACAGGTTTCAAGGGTTTATCACGCTTTATTCGAATGATTGATAAAGTTTTAGAAAATGAAAATGATTTGGCAG
ATGTTGAGGTGGCATTACCGCAAAATGCTGTTAACCTAATGACTATACACAAATCAAAGGGGCTTGAGTTTAAGTATGTA
TTTATTTTAAATATTGATAAGAAATTTTCAATGGTAGACATAACTTCCCCTCTTATTTTAAGCCGAAATCAAGGAATTGG
TATTAAATATGTTGCTGATATGCGACATGAACTCGAAGAAGAGATACTGCCTGCAGTAAAGGTTAGCATGGAAACACTTC
CTTACCAACTTAATAAAAGAGAGTTACGCTTAGCTACTTTATCAGAGCAAATGCGTTTACTTTACGTAGCTATGACACGT
GCAGAGAAAAAATTATATCTGGTTGGTAAGGCTAGTCAAACCAAATGGGCTGATCATTATGACTTAGTATCTGAAAATAA
TCATCTCCCATTAGCTAGTCGTGAGACTTTTGTGACCTTTCAAGATTGGTTACTGGCTGTTCATGAAACCTATAAGAAAC
AAGAGTTGTTTTATGACATCAACTTCGTATCATTAGAGGAATTAACAGATCACCACATAGGGATGGTTAATCCTAGTCTA
CCTTTCAATCCCGATAATAAGGCAGAGAATCGTCAGTCTGAAGATATCGTGCGCGCGATTAGCGTGTTAGAATCTGTTGA
ACAGATTAATCAAACTTATAAAGCGGCTATTGAGTTACCGACAGTAAGAACACCAAGTCAAGTCAAAAAATTCTATGAGC
CTATTCTAGATATAGAAGGCGTTGATGTGATGGAAACTATTACTAAAACATCAGTAGATTTTAAGTTACCTGATTTTTCT
ACAAGTAAAAAGCAAGACCCAGCAGCTTTAGGATCTGCTGTACATGAATTAATGCAACGCATAGAGATGTCATCTCATGT
CAAAATGGAAGATATTCAAAAAGCCTTGACAGAAGTGAATGCTGAAACAAGTGTCAAAGCGGCTATTCAGATTGAAAAAA
TCAACTATTTTTTCCAAGAAACCTCACTCGGTAAATATATACAAGAAGAAGTAGAACATCTACATCGAGAGGCACCTTTT
GCCATGTTAAAAGAAGATCCGGAGAGTGGTGAGAAATTCGTTGTACGTGGTATTATTGATGGGTATCTACTATTAGAAAA
TCGGATAATTCTATTTGATTATAAGACTGATAAATTTGTCAATCCTCTGGAATTAAAAGAACGCTATCAGGGACAAATGG
CTTTATATGCAGAAGCTTTAAAAAAATCTTACGAGATAGAAAAGATAGACAAATACTTAATTCTTTTAGGTGGTAAACAG
CTAGAAGTGGTAAAAATGGATTAA

Domains

Predicted by InterProScan.

• UvrD-like helicase C-terminal domain (UvrD_C) (473-888)

• PD-(D/E)XK nuclease superfamily (PDDEXK_1) (1036-1185)

• UvrD/REP helicase N-terminal domain (UvrD-helicase) (29-464)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
rexA	Streptococcus pneumoniae R6	50.244	100	0.513