Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   POF65_RS06525 Genome accession   NZ_CP116706
Coordinates   1255048..1255530 (-) Length   160 a.a.
NCBI ID   WP_000163512.1    Uniprot ID   Q8DZB3
Organism   Streptococcus agalactiae strain A909 sCas9     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1250048..1260530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  POF65_RS06505 (POF65_06505) alsS 1250307..1251989 (-) 1683 WP_000140344.1 acetolactate synthase AlsS -
  POF65_RS06510 (POF65_06510) - 1252099..1253325 (-) 1227 WP_000934872.1 hypothetical protein -
  POF65_RS06515 (POF65_06515) - 1253315..1254505 (-) 1191 WP_001081538.1 AI-2E family transporter -
  POF65_RS06520 (POF65_06520) - 1254597..1255058 (-) 462 WP_000796050.1 NUDIX hydrolase -
  POF65_RS06525 (POF65_06525) mutX 1255048..1255530 (-) 483 WP_000163512.1 8-oxo-dGTP diphosphatase Machinery gene
  POF65_RS06530 (POF65_06530) hylB 1255749..1258994 (+) 3246 WP_000403396.1 hyaluronate lyase -
  POF65_RS06535 (POF65_06535) rfbB 1259046..1260092 (-) 1047 WP_000134281.1 dTDP-glucose 4,6-dehydratase -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 18837.23 Da        Isoelectric Point: 4.5116

>NTDB_id=711048 POF65_RS06525 WP_000163512.1 1255048..1255530(-) (mutX) [Streptococcus agalactiae strain A909 sCas9]
MTKLATICYIDNGKELLLLHRNKKENDVHEGKWISVGGKLEAGETPDECAKREILEETHLTVKKMDFKGVITFPEFTPGH
DWYTYVFKVTDYEGELISDDESREGTLEWVPYDQVLSKPTWQGDYEIFKWILEDVPFFSAKFVYDEHQNLIEKTVNFYEK

Nucleotide


Download         Length: 483 bp        

>NTDB_id=711048 POF65_RS06525 WP_000163512.1 1255048..1255530(-) (mutX) [Streptococcus agalactiae strain A909 sCas9]
ATGACTAAATTAGCAACAATTTGTTACATTGACAATGGCAAGGAATTACTTCTATTGCACCGCAACAAAAAAGAGAATGA
TGTTCATGAGGGAAAGTGGATCTCGGTAGGCGGTAAACTGGAGGCAGGTGAAACTCCTGATGAATGTGCTAAGCGTGAAA
TTCTAGAAGAAACCCATTTAACAGTAAAAAAAATGGATTTTAAAGGAGTCATCACTTTTCCTGAATTTACGCCAGGTCAT
GATTGGTATACCTATGTCTTTAAAGTAACAGATTATGAAGGAGAGTTAATTTCAGATGATGAATCACGAGAAGGAACCTT
AGAATGGGTACCATATGATCAAGTTCTCTCTAAGCCAACGTGGCAAGGAGATTACGAAATTTTTAAATGGATTTTAGAAG
ATGTTCCTTTCTTTTCTGCTAAGTTTGTTTATGATGAACACCAAAATTTAATTGAAAAGACGGTTAATTTTTATGAAAAA
TAG

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(3-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DZB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

71.698

99.375

0.712