Detailed information NTG0710233

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NKW85_RS04855
• Genome accession: NZ_CP101498
• Coordinates: 1069686..1070729 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain QB7
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1064686..1075729

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NKW85_RS04830 (NKW85_04830)	-	1065689..1066408 (+)	720	WP_023015863.1	glutamine amidotransferase	-
NKW85_RS04835 (NKW85_04835)	-	1066491..1067477 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
NKW85_RS04840 (NKW85_04840)	map	1067697..1068461 (+)	765	WP_002481666.1	type I methionyl aminopeptidase	-
NKW85_RS04845 (NKW85_04845)	-	1068577..1068972 (+)	396	WP_002481665.1	hypothetical protein	-
NKW85_RS04850 (NKW85_04850)	liaF	1068988..1069689 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
NKW85_RS04855 (NKW85_04855)	vraS	1069686..1070729 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
NKW85_RS04860 (NKW85_04860)	vraR	1070719..1071348 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
NKW85_RS04865 (NKW85_04865)	-	1071419..1071997 (-)	579	WP_002481661.1	carbonic anhydrase	-
NKW85_RS04870 (NKW85_04870)	-	1072206..1073282 (-)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
NKW85_RS04875 (NKW85_04875)	-	1073413..1073703 (-)	291	WP_002481659.1	hypothetical protein	-
NKW85_RS04880 (NKW85_04880)	-	1073711..1074175 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
NKW85_RS04885 (NKW85_04885)	-	1074399..1074605 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=710233 NKW85_RS04855 WP_002481663.1 1069686..1070729(+) (vraS) [Staphylococcus simulans strain QB7]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=710233 NKW85_RS04855 WP_002481663.1 1069686..1070729(+) (vraS) [Staphylococcus simulans strain QB7]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTATACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTATTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATTGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862