Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NKW85_RS04550 Genome accession   NZ_CP101498
Coordinates   1008827..1009543 (-) Length   238 a.a.
NCBI ID   WP_023015910.1    Uniprot ID   -
Organism   Staphylococcus simulans strain QB7     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1003827..1014543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NKW85_RS04530 (NKW85_04530) - 1004972..1005613 (+) 642 WP_002481727.1 redox-sensing transcriptional repressor Rex -
  NKW85_RS04535 (NKW85_04535) - 1005664..1005888 (-) 225 WP_002481726.1 sulfurtransferase TusA family protein -
  NKW85_RS04540 (NKW85_04540) - 1005944..1007032 (-) 1089 WP_023015912.1 YeeE/YedE family protein -
  NKW85_RS04545 (NKW85_04545) - 1007268..1008752 (+) 1485 WP_023015911.1 GH32 C-terminal domain-containing protein -
  NKW85_RS04550 (NKW85_04550) agrA 1008827..1009543 (-) 717 WP_023015910.1 quorum-sensing response regulator AgrA Regulator
  NKW85_RS04555 (NKW85_04555) agrC 1009546..1010847 (-) 1302 WP_023015909.1 quorum-sensing sensor histidine kinase AgrC -
  NKW85_RS04560 (NKW85_04560) agrD 1010887..1011024 (-) 138 WP_023015908.1 cyclic lactone autoinducer peptide AgrD -
  NKW85_RS04565 (NKW85_04565) - 1011024..1011602 (-) 579 WP_002481720.1 accessory gene regulator AgrB -
  NKW85_RS04570 (NKW85_04570) - 1011914..1012078 (+) 165 WP_158257062.1 delta-lysin family phenol-soluble modulin -
  NKW85_RS04575 (NKW85_04575) - 1012386..1013183 (-) 798 WP_023015907.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27761.60 Da        Isoelectric Point: 4.7718

>NTDB_id=710232 NKW85_RS04550 WP_023015910.1 1008827..1009543(-) (agrA) [Staphylococcus simulans strain QB7]
MKIIICEDDVQQREHIESIIENYIMIEEKPLEVALSTGDPYKVLEFAKATNEICCYFLDIQLDSDINGIKLGSELRNYDS
VGSIIFITSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESSLETIELKRGSNSVYVNYDDVM
FFESSAKSHRLIAHLDNRQIEFYGNLKDLSQLDDRFFRCHNSYVINRNNIEEVISKEREVYFKNGEHCYISVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=710232 NKW85_RS04550 WP_023015910.1 1008827..1009543(-) (agrA) [Staphylococcus simulans strain QB7]
GTGAAGATTATTATATGCGAAGATGATGTACAACAGCGTGAACACATTGAATCCATCATTGAAAATTATATTATGATTGA
AGAAAAACCTTTAGAAGTGGCGCTATCAACGGGTGATCCTTATAAGGTATTAGAATTCGCTAAAGCTACAAATGAGATTT
GTTGTTACTTCTTAGATATTCAGTTAGATTCTGATATTAACGGTATTAAGCTTGGCAGCGAACTTAGAAACTATGATTCT
GTCGGCAGTATTATCTTTATTACTAGCCACAGTGAACTCACTTATCTTACTTTCGTTTATAAAGTAGCAGCCATGGACTT
TATTTTTAAAGATGACCCTTCAGAAATGAAATCTCGAATTATTGATTGTATCGAAACTGCATTGACGAGACTACAGTTGC
TTTCAAAAGAATCTAGTCTCGAAACAATTGAGTTAAAACGTGGCAGTAACTCAGTCTATGTTAATTACGATGATGTCATG
TTCTTTGAATCCTCGGCAAAATCACATCGCTTAATTGCGCATTTAGACAATCGTCAAATCGAATTTTATGGCAACTTAAA
AGATTTAAGCCAATTAGATGACCGCTTCTTCCGTTGTCACAATAGTTACGTCATTAATCGCAATAACATCGAAGAAGTAA
TATCTAAAGAACGTGAGGTCTACTTTAAAAATGGTGAACACTGTTATATCTCAGTAAGAAATTTAAAGAAAATCTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

78.992

100

0.79