Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   PFZ59_RS02380 Genome accession   NZ_CP116393
Coordinates   465966..467903 (-) Length   645 a.a.
NCBI ID   WP_277697413.1    Uniprot ID   -
Organism   Streptococcus suis strain SS/UPM/MY/F001     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 460966..472903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFZ59_RS02355 (PFZ59_02355) spx 461224..461622 (-) 399 WP_002939362.1 transcriptional regulator Spx -
  PFZ59_RS02360 (PFZ59_02360) recA 461858..463009 (-) 1152 WP_277697409.1 recombinase RecA Machinery gene
  PFZ59_RS02365 (PFZ59_02365) cinA 463061..464242 (-) 1182 WP_277697410.1 competence/damage-inducible protein A Machinery gene
  PFZ59_RS02370 (PFZ59_02370) - 464279..464848 (-) 570 WP_277697411.1 DNA-3-methyladenine glycosylase I -
  PFZ59_RS02375 (PFZ59_02375) ruvA 465337..465927 (-) 591 WP_277697412.1 Holliday junction branch migration protein RuvA Machinery gene
  PFZ59_RS02380 (PFZ59_02380) hexB 465966..467903 (-) 1938 WP_277697413.1 DNA mismatch repair endonuclease MutL Machinery gene
  PFZ59_RS02385 (PFZ59_02385) - 468021..469544 (-) 1524 WP_277697414.1 quinol oxidase -
  PFZ59_RS02390 (PFZ59_02390) - 469735..470955 (-) 1221 WP_277697415.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  PFZ59_RS02395 (PFZ59_02395) - 471161..471307 (-) 147 WP_208582737.1 hypothetical protein -
  PFZ59_RS02400 (PFZ59_02400) - 471469..472725 (+) 1257 WP_277697764.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72905.17 Da        Isoelectric Point: 5.1693

>NTDB_id=709836 PFZ59_RS02380 WP_277697413.1 465966..467903(-) (hexB) [Streptococcus suis strain SS/UPM/MY/F001]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQIIVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFVLVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREATSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=709836 PFZ59_RS02380 WP_277697413.1 465966..467903(-) (hexB) [Streptococcus suis strain SS/UPM/MY/F001]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAATCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTCAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCCTCCATTGCTTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTATTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCCTT
TGTCTTAGTAAACGAAGGGCGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCCGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAACGGTCGTTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTACGGAAGTAAGTTGATGGTTGGACGCTTTCCGTTGGCAGTCATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGTGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGCGACCTCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCGCAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCCTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGATGCCCTTCGTCAAGTTGGTGTCAACTTAGAAGAATACGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGTATCTACGAGATGTGCGACATGTTGCTTCTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCAATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GCCCAGTCTTAGTACATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGA
GAGTTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(447-589)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.462

100

0.73