Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NMJ60_RS10705 Genome accession   NZ_CP101314
Coordinates   2137435..2138151 (+) Length   238 a.a.
NCBI ID   WP_000688493.1    Uniprot ID   G9IE49
Organism   Staphylococcus aureus strain #492     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2132435..2143151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMJ60_RS10675 - 2132652..2133278 (+) 627 WP_000522381.1 nitroreductase family protein -
  NMJ60_RS10680 - 2133639..2134424 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  NMJ60_RS14320 hld 2135024..2135104 (-) 81 WP_000046022.1 delta-hemolysin -
  NMJ60_RS10690 - 2135394..2135957 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  NMJ60_RS10695 agrD 2135960..2136103 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  NMJ60_RS10700 agrC 2136133..2137416 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  NMJ60_RS10705 agrA 2137435..2138151 (+) 717 WP_000688493.1 quorum-sensing response regulator AgrA Regulator
  NMJ60_RS10710 - 2138226..2138335 (+) 110 Protein_2074 hypothetical protein -
  NMJ60_RS10715 - 2138523..2139482 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  NMJ60_RS10720 - 2139479..2140963 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  NMJ60_RS10725 - 2141112..2142062 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27920.92 Da        Isoelectric Point: 6.3009

>NTDB_id=709655 NMJ60_RS10705 WP_000688493.1 2137435..2138151(+) (agrA) [Staphylococcus aureus strain #492]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKK

Nucleotide


Download         Length: 717 bp        

>NTDB_id=709655 NMJ60_RS10705 WP_000688493.1 2137435..2138151(+) (agrA) [Staphylococcus aureus strain #492]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAAATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-236)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G9IE49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

99.58

0.996