Detailed information NTG0708937

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: PIC88_RS22750
• Genome accession: NZ_CP116188
• Coordinates: 4668312..4669337 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain DETEC-E223
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4663312..4674337

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PIC88_RS22730 (PIC88_22725)	metJ	4664373..4664690 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
PIC88_RS22735 (PIC88_22730)	yiiX	4664874..4665482 (+)	609	WP_000797353.1	YiiX family permuted papain-like enzyme	-
PIC88_RS22740 (PIC88_22735)	rpmE	4665543..4665755 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
PIC88_RS22745 (PIC88_22740)	priA	4665958..4668156 (+)	2199	WP_001333520.1	primosomal protein N'	Machinery gene
PIC88_RS22750 (PIC88_22745)	cytR	4668312..4669337 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
PIC88_RS22755 (PIC88_22750)	ftsN	4669429..4670388 (+)	960	WP_000068828.1	cell division protein FtsN	-
PIC88_RS22760 (PIC88_22755)	hslV	4670481..4671011 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
PIC88_RS22765 (PIC88_22760)	hslU	4671021..4672352 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
PIC88_RS22770 (PIC88_22765)	menA	4672419..4673345 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
PIC88_RS22775 (PIC88_22770)	rraA	4673438..4673923 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
PIC88_RS22780 (PIC88_22775)	zapB	4674008..4674253 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=708937 PIC88_RS22750 WP_000644904.1 4668312..4669337(+) (cytR) [Escherichia coli strain DETEC-E223]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=708937 PIC88_RS22750 WP_000644904.1 4668312..4669337(+) (cytR) [Escherichia coli strain DETEC-E223]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAGCTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628