Detailed information NTG0070889

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: H7678_RS10150
• Genome accession: NZ_AP023393
• Coordinates: 2081722..2084277 (-)
• Length: 851 a.a.
• NCBI ID: WP_003061429.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain 89
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2076722..2089277

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7678_RS10125 (SDSE89_19860)	-	2076850..2077203 (-)	354	WP_003061807.1	VOC family protein	-
H7678_RS10130 (SDSE89_19870)	-	2077206..2077778 (-)	573	WP_003058799.1	DNA-3-methyladenine glycosylase I	-
H7678_RS10135 (SDSE89_19880)	ruvA	2077788..2078381 (-)	594	WP_003058778.1	Holliday junction branch migration protein RuvA	Machinery gene
H7678_RS10140 (SDSE89_19890)	-	2078383..2079603 (-)	1221	WP_003058727.1	MFS transporter	-
H7678_RS10145 (SDSE89_19900)	hexB	2079614..2081596 (-)	1983	WP_003060855.1	DNA mismatch repair endonuclease MutL	Machinery gene
H7678_RS10150 (SDSE89_19910)	hexA	2081722..2084277 (-)	2556	WP_003061429.1	DNA mismatch repair protein MutS	Machinery gene
H7678_RS10155 (SDSE89_19920)	-	2084264..2084617 (-)	354	WP_003062220.1	YlbF family regulator	-
H7678_RS10160 (SDSE89_19930)	argR	2084614..2085051 (-)	438	WP_003055516.1	arginine repressor	-
H7678_RS10165 (SDSE89_19940)	argS	2085340..2087031 (+)	1692	WP_015017500.1	arginine--tRNA ligase	-
H7678_RS10170 (SDSE89_19950)	-	2087101..2088498 (-)	1398	WP_003062372.1	ATP-binding cassette domain-containing protein	-

Sequence

Protein

• Length: 851 a.a.
• Molecular weight: 95312.77 Da
• Isoelectric Point: 4.8806

>NTDB_id=70889 H7678_RS10150 WP_003061429.1 2081722..2084277(-) (hexA) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
MAKANISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFNSPFVDKLVNDIDSLPELEYLIRTAIDP
DAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAAVAETNHYIRPQFN
DNHVIKIQEGRHAVVEKVMGVQEYIPNSISFNQETSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTMFATHYHEL
TELSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPEALLSRADEVLTRLEAQAQSAEIISVPSKV
EPSSAAREGQLSLFPDEDKSQEIIHTLEAIDVMNMTPLQAMTTLYELKKLL

Nucleotide

• Length: 2556 bp

>NTDB_id=70889 H7678_RS10150 WP_003061429.1 2081722..2084277(-) (hexA) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
ATGGCAAAAGCTAACATTTCTCCTGGGATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
CAGGATGGGTGACTTTTATGAATTATTTTATGATGATGCTGTCAAGGCAGCGCAACTTTTAGAGATTGGTTTGACCAGTC
GCAACAAGAATGCGGAAAATCCAATTCCCATGGCAGGAGTGCCACATCATTCTGCCCAGCAATACATTGATGTGTTAATT
GAGTTGGGTTATAAGGTTGCTGTCGCAGAACAAATGGAAGACCCAAAGCAAGCTGTTGGGGTGGTGAAGCGTGAGGTCGT
TCAAGTCATAACTCCTGGAACGGTTGTGGATTCAGCTAAGCCAGATAGCGCCAATAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTGCCGTTATGGATTGGCTTATATGGATGTGTCCACAGGTGAATTTTGCGTGACAGATTTGGCGGACTTTACGAGT
GTTCGTAGCGAAATCCAAAACCTCAAGGCAAAAGAAGTCTTACTAGGTTTTGATTTATCTGAAGAAGAACAGACGATTTT
GGTCAAGCAGATGAATTTGCTGCTTTCTTATGAAGAAACGGTCTATGAAGATAAATCTTTAATTGACGGTCAATTGACAA
CGGTAGAACTGACAGCGGCAGGAAAACTCTTGCAATACGTTCACAAAACACAAATGCGAGAACTCAGCCACTTGCAAGCC
TTGGTTCACTATGAAATCAAGGATTATTTGCAGATGTCGTATGCCACTAAGTCAAGTCTAGATTTGGTAGAGAATGCTAG
AACGAATAAAAAACATGGGAGTCTGTATTGGCTGTTAGATGAAACCAAGACAGCTATGGGGATGAGGCTTTTGCGCTCAT
GGATTGATCGACCTTTGGTTTCTAAAGAAGCTATTTTAGAGCGTCAAGAAATTATTCAAGTTTTTCTGAATGCTTTTATT
GAGCGAACAGATTTAAGCAATAGCTTAAAAGGTGTTTACGATATCGAACGCTTATCTAGCCGTGTGTCTTTTGGCAAGGC
AAATCCGAAAGATTTACTTCAATTGGGGCATACCTTAGCCCAAGTGCCTTATATCAAAGCTATCTTAGAGTCTTTTAATA
GTCCTTTTGTTGACAAACTTGTCAATGATATTGACAGTTTGCCTGAGTTGGAATACTTGATTAGAACAGCCATTGATCCA
GATGCACCAGCAACTATTAGTGAAGGAAGTATTATCCGCAATGGTTTTGATGAGCGCTTGGACCATTATCGTAAAGTAAT
GCGAGAGGGGACAGGCTGGATTGCGGATATTGAGGCCAAAGAGCGTCAAGCAAGTGGCATTAATAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTTCACGTTACGAATTCAAATCTTAGCTTAGTTCCCGACCATTTTTTCAGAAAGGCA
ACTTTAAAAAATTCTGAGCGTTATGGAACAGCAGAATTGGCTAAGATTGAAGGTCAGATGTTAGAGGCTAGGGAAGAGTC
ATCTAGTTTAGAATACGATATTTTTATGTGTATTCGAGCTCAAGTTGAAACCTATATTAATCGTTTACAGAAACTGGCTA
AAACTTTGGCAACGGTGGATGTTTTGCAAAGTTTAGCAGCCGTTGCCGAAACCAATCATTATATCCGGCCGCAGTTCAAT
GATAATCATGTGATTAAAATTCAAGAAGGTCGTCACGCGGTTGTTGAAAAGGTTATGGGAGTGCAGGAATACATTCCCAA
TAGTATCTCTTTTAACCAAGAGACAAGCATTCAATTGATTACAGGTCCAAATATGAGCGGTAAGTCGACTTATATGAGAC
AGCTGGCCTTAACGGTTATCATGGCTCAGATGGGCTCATTTGTAGCTGCTGACCATGTTGATTTGCCTCTATTTGATGCG
ATTTTTACGCGTATTGGGGCTGCTGATGATTTGATTTCTGGGCAATCAACCTTTATGGTGGAGATGATGGAAGCAAACCA
AGCAATCAAACGAGCCAGTGACAATTCCCTTATTCTATTTGATGAACTAGGGAGGGGTACGGCAACTTATGATGGTATGG
CACTGGCTCAGGCAATTATCGAATATATCCATGATAGAGTTGGTGCTAAGACCATGTTTGCAACGCACTATCATGAGTTG
ACAGAATTGTCAACTAAGTTGACAAGTCTAGTCAATGTTCATGTAGCAACGCTTGAAAAAGATGGCGATGTAACCTTCCT
TCATAAGATTGCTGAGGGACCGGCGGATAAATCTTACGGTATTCATGTAGCAAAAATAGCAGGACTTCCTGAGGCCCTGC
TAAGCAGAGCAGATGAGGTGCTTACGCGTTTAGAAGCGCAAGCACAATCTGCTGAGATAATATCAGTCCCTTCAAAAGTT
GAGCCAAGCAGCGCTGCTAGAGAGGGACAGTTATCGCTGTTTCCTGATGAGGATAAGTCTCAGGAGATTATTCACACGTT
AGAAGCTATTGATGTGATGAACATGACTCCACTTCAAGCAATGACAACCCTTTACGAATTGAAAAAGTTGTTATAG

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.093	100	0.711
mutS	Pseudomonas stutzeri strain ATCC 17587	36.959	100	0.371