Detailed information NTG0070834

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: K6J55_RS03645
• Genome accession: NZ_AP018767
• Coordinates: 724910..726130 (+)
• Length: 406 a.a.
• NCBI ID: WP_048942289.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain CHBN-II-4 isolate 13H33
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 719910..731130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6J55_RS03625 (CHBNII4_06870)	corC	720873..721772 (-)	900	WP_005656283.1	CNNM family magnesium/cobalt transport protein CorC	-
K6J55_RS03630 (CHBNII4_06880)	ampD	722394..722957 (-)	564	WP_048942277.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
K6J55_RS03635 (CHBNII4_06890)	pilA	723073..723522 (+)	450	WP_048942287.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
K6J55_RS03640 (CHBNII4_06900)	pilB	723519..724913 (+)	1395	WP_110459385.1	GspE/PulE family protein	Machinery gene
K6J55_RS03645 (CHBNII4_06910)	pilC	724910..726130 (+)	1221	WP_048942289.1	type II secretion system F family protein	Machinery gene
K6J55_RS03650 (CHBNII4_06920)	pilD	726127..726819 (+)	693	WP_048942290.1	A24 family peptidase	Machinery gene
K6J55_RS03655 (CHBNII4_06930)	rho	726873..728135 (-)	1263	WP_005648966.1	transcription termination factor Rho	-
K6J55_RS03660 (CHBNII4_06940)	metJ	728383..728700 (+)	318	WP_005631186.1	met regulon transcriptional regulator MetJ	-
K6J55_RS03665 (CHBNII4_06950)	cueR	728714..729100 (-)	387	WP_005648963.1	Cu(I)-responsive transcriptional regulator	-
K6J55_RS03670 (CHBNII4_06960)	-	729177..729383 (+)	207	WP_005666692.1	heavy-metal-associated domain-containing protein	-
K6J55_RS03675 (CHBNII4_06970)	-	729469..729675 (+)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-
K6J55_RS03680 (CHBNII4_06980)	-	729749..729955 (+)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-
K6J55_RS03685 (CHBNII4_06990)	-	730029..730235 (+)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-

Sequence

Protein

• Length: 406 a.a.
• Molecular weight: 46305.62 Da
• Isoelectric Point: 9.9010

>NTDB_id=70834 K6J55_RS03645 WP_048942289.1 724910..726130(+) (pilC) [Haemophilus influenzae strain CHBN-II-4 isolate 13H33]
MTKKLFYYQASNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTHIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQIKKTLVNDIILDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide

• Length: 1221 bp

>NTDB_id=70834 K6J55_RS03645 WP_048942289.1 724910..726130(+) (pilC) [Haemophilus influenzae strain CHBN-II-4 isolate 13H33]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGCGAATTACTCAATCAATTAGCCACATTGCTACAATCCGCAATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCACATTATGCTCAATGAATGGCTTGAACGACTGCTTCAATCGATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTGTTAGGAATTTCACTATTACTAACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCTGAGTTACCGACAATCACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAATCAAGAAAACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAACATATTGCGGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGCAGTCTGATTGGGATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGATCAGTTATTCAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (63-185)

• Type II secretion system (T2SS), protein F (T2SSF) (266-397)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Haemophilus influenzae Rd KW20	98.522	100	0.985
pilC	Haemophilus influenzae 86-028NP	97.783	100	0.978
pilC	Glaesserella parasuis strain SC1401	38.155	98.768	0.377