Detailed information NTG0707466

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: PIC49_RS22630
• Genome accession: NZ_CP116074
• Coordinates: 4714985..4716010 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain DETEC-S586
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4709985..4721010

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PIC49_RS22610 (PIC49_22615)	metJ	4711170..4711487 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
PIC49_RS22615 (PIC49_22620)	yiiX	4711547..4712155 (+)	609	WP_000702318.1	YiiX family permuted papain-like enzyme	-
PIC49_RS22620 (PIC49_22625)	rpmE	4712216..4712428 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
PIC49_RS22625 (PIC49_22630)	priA	4712631..4714829 (+)	2199	WP_001309891.1	primosomal protein N'	Machinery gene
PIC49_RS22630 (PIC49_22635)	cytR	4714985..4716010 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
PIC49_RS22635 (PIC49_22640)	ftsN	4716102..4717061 (+)	960	WP_000068844.1	cell division protein FtsN	-
PIC49_RS22640 (PIC49_22645)	hslV	4717154..4717684 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
PIC49_RS22645 (PIC49_22650)	hslU	4717694..4719025 (+)	1332	WP_001293344.1	HslU--HslV peptidase ATPase subunit	-
PIC49_RS22650 (PIC49_22655)	menA	4719092..4720018 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
PIC49_RS22655 (PIC49_22660)	rraA	4720111..4720596 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=707466 PIC49_RS22630 WP_000644904.1 4714985..4716010(+) (cytR) [Escherichia coli strain DETEC-S586]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=707466 PIC49_RS22630 WP_000644904.1 4714985..4716010(+) (cytR) [Escherichia coli strain DETEC-S586]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGACGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCAATGCAACAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCGCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628