Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIC30_RS10205 Genome accession   NZ_CP116071
Coordinates   2128363..2129019 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain DETEC-S589     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2123363..2134019
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC30_RS10175 (PIC30_10175) dcyD 2124242..2125228 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  PIC30_RS10180 (PIC30_10180) tcyL 2125243..2125911 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PIC30_RS10185 (PIC30_10185) tcyN 2125908..2126660 (+) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PIC30_RS10190 (PIC30_10190) sdiA 2126890..2127612 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  PIC30_RS10195 (PIC30_10195) yecF 2127680..2127904 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PIC30_RS10200 (PIC30_10200) yecU 2127891..2128067 (-) 177 WP_001307856.1 protein YecU -
  PIC30_RS10205 (PIC30_10205) letA 2128363..2129019 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PIC30_RS10210 (PIC30_10210) uvrC 2129016..2130848 (+) 1833 WP_001283418.1 excinuclease ABC subunit UvrC Machinery gene
  PIC30_RS10215 (PIC30_10215) pgsA 2130905..2131453 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PIC30_RS10235 (PIC30_10235) yecA 2132103..2132768 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=707350 PIC30_RS10205 WP_000611328.1 2128363..2129019(+) (letA) [Escherichia coli strain DETEC-S589]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=707350 PIC30_RS10205 WP_000611328.1 2128363..2129019(+) (letA) [Escherichia coli strain DETEC-S589]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482