Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIC30_RS00155 Genome accession   NZ_CP116071
Coordinates   28552..29142 (+) Length   196 a.a.
NCBI ID   WP_001332271.1    Uniprot ID   A0A0H2Z4C4
Organism   Escherichia coli strain DETEC-S589     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 23552..34142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC30_RS00120 (PIC30_00120) yidG 23844..24206 (+) 363 WP_001113443.1 DUF202 domain-containing protein -
  PIC30_RS00125 (PIC30_00125) yidF 24203..24700 (+) 498 WP_000148034.1 radical SAM protein -
  PIC30_RS00130 (PIC30_00130) emrD 24708..25892 (-) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  PIC30_RS00135 (PIC30_00135) ysdE 25974..26048 (+) 75 WP_211180519.1 protein YsdE -
  PIC30_RS00140 (PIC30_00140) ivbL 26293..26391 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  PIC30_RS00145 (PIC30_00145) ilvB 26497..28185 (+) 1689 WP_000168473.1 acetolactate synthase large subunit -
  PIC30_RS00150 (PIC30_00150) ilvN 28189..28479 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PIC30_RS00155 (PIC30_00155) letA 28552..29142 (+) 591 WP_001332271.1 transcriptional regulator UhpA Regulator
  PIC30_RS00160 (PIC30_00160) uhpB 29142..30644 (+) 1503 WP_001332272.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PIC30_RS00165 (PIC30_00165) uhpC 30654..31973 (+) 1320 WP_214209369.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PIC30_RS00170 (PIC30_00170) uhpT 32111..33502 (+) 1392 WP_271287406.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20836.26 Da        Isoelectric Point: 5.6059

>NTDB_id=707310 PIC30_RS00155 WP_001332271.1 28552..29142(+) (letA) [Escherichia coli strain DETEC-S589]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGCGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=707310 PIC30_RS00155 WP_001332271.1 28552..29142(+) (letA) [Escherichia coli strain DETEC-S589]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGTGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2Z4C4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378