Detailed information NTG0706971

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: PF977_RS22130
• Genome accession: NZ_CP116012
• Coordinates: 4199088..4200170 (-)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain SRCM124333
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4194088..4205170

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PF977_RS22105 (PF977_22105)	cysE	4194193..4194846 (-)	654	WP_003225749.1	serine O-acetyltransferase	-
PF977_RS22110 (PF977_22110)	gltX	4195148..4196599 (-)	1452	WP_014478617.1	glutamate--tRNA ligase	-
PF977_RS22115 (PF977_22115)	ispF	4196690..4197166 (-)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
PF977_RS22120 (PF977_22120)	ispD	4197159..4197857 (-)	699	WP_015252991.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
PF977_RS22125 (PF977_22125)	yacL	4197872..4198972 (-)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
PF977_RS22130 (PF977_22130)	disA	4199088..4200170 (-)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
PF977_RS22135 (PF977_22135)	radA/sms	4200174..4201550 (-)	1377	WP_015715115.1	DNA repair protein RadA	Machinery gene
PF977_RS22140 (PF977_22140)	clpC	4201642..4204074 (-)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
PF977_RS22145 (PF977_22145)	mcsB	4204071..4205162 (-)	1092	WP_003235007.1	protein arginine kinase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=706971 PF977_RS22130 WP_003225736.1 4199088..4200170(-) (disA) [Bacillus subtilis strain SRCM124333]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=706971 PF977_RS22130 WP_003225736.1 4199088..4200170(-) (disA) [Bacillus subtilis strain SRCM124333]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGCTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCTGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTACCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGATAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1