Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   PF977_RS13360 Genome accession   NZ_CP116012
Coordinates   2531857..2533740 (-) Length   627 a.a.
NCBI ID   WP_064911511.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM124333     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2526857..2538740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PF977_RS13330 (PF977_13330) fabD 2527447..2528313 (-) 867 WP_015715909.1 ACP S-malonyltransferase -
  PF977_RS13335 (PF977_13335) - 2528310..2528576 (-) 267 WP_120363368.1 hypothetical protein -
  PF977_RS13340 (PF977_13340) pksB 2528687..2529364 (-) 678 WP_015715908.1 MBL fold metallo-hydrolase -
  PF977_RS13345 (PF977_13345) pksA 2529554..2530171 (-) 618 WP_015715907.1 TetR/AcrR family transcriptional regulator -
  PF977_RS13350 (PF977_13350) - 2530292..2530849 (+) 558 WP_015715906.1 hypothetical protein -
  PF977_RS13355 (PF977_13355) ymzD 2531004..2531459 (+) 456 WP_074794242.1 regulatory YrvL family protein -
  PF977_RS13360 (PF977_13360) hexB 2531857..2533740 (-) 1884 WP_064911511.1 DNA mismatch repair endonuclease MutL Machinery gene
  PF977_RS13365 (PF977_13365) hexA 2533756..2536332 (-) 2577 WP_064911512.1 DNA mismatch repair protein MutS Machinery gene
  PF977_RS13370 (PF977_13370) cotE 2536465..2537010 (-) 546 WP_003231833.1 outer spore coat protein CotE -
  PF977_RS13375 (PF977_13375) ymcA 2537272..2537703 (-) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70599.49 Da        Isoelectric Point: 5.6795

>NTDB_id=706904 PF977_RS13360 WP_064911511.1 2531857..2533740(-) (hexB) [Bacillus subtilis strain SRCM124333]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPAIKNEQQFITFDEKPPERKVPEKAHAPSYSPMKLSSVVKEPVDAEEELPPLQFDAPPI
VDQEQTLEVSDVSEEQLETFEQECHEEQQQPASDRVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQEMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=706904 PF977_RS13360 WP_064911511.1 2531857..2533740(-) (hexB) [Bacillus subtilis strain SRCM124333]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGAACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACGGATGTGGTTAACCGTATTGCTCTTGCGCATCCAGAGGTATCGATTCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAATGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCTTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTGAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCAATTACCTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATACGTGACGGA
ATTAAAGATGTGTTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCGGCACCTGCCATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAGAAAAGTACCGGAAAAAGCGCATGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGGTTGATGCGGAGGAAGAATTGCCTCCTCTCCAATTTGATGCTCCACCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGAAGAACAGCTTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCAGCAGCCAGCGTCTGATCGGGTTCCAATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTATATATTATCGATCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTCCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTCCAGGAGATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTCATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGACGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATTCACC
ACTCGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(442-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.497

100

0.467