Detailed information NTG0706207

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: PCM89_RS13230
• Genome accession: NZ_CP115887
• Coordinates: 2644867..2646984 (+)
• Length: 705 a.a.
• NCBI ID: WP_001063343.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain C308
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2639867..2651984

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PCM89_RS13205 (PCM89_13205)	-	2639938..2640156 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
PCM89_RS13210 (PCM89_13210)	-	2640545..2640976 (+)	432	WP_000455858.1	CHAP domain-containing protein	-
PCM89_RS13215 (PCM89_13215)	-	2641115..2642392 (-)	1278	WP_001180327.1	hydroxymethylglutaryl-CoA reductase, degradative	-
PCM89_RS13220 (PCM89_13220)	-	2642646..2643812 (+)	1167	WP_000151986.1	hydroxymethylglutaryl-CoA synthase	-
PCM89_RS13225 (PCM89_13225)	-	2643983..2644504 (-)	522	WP_000262592.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
PCM89_RS13230 (PCM89_13230)	clpE	2644867..2646984 (+)	2118	WP_001063343.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
PCM89_RS13235 (PCM89_13235)	-	2647051..2647221 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
PCM89_RS13240 (PCM89_13240)	feoB	2647234..2649228 (-)	1995	WP_000432895.1	ferrous iron transport protein B	-
PCM89_RS13245 (PCM89_13245)	-	2649240..2649467 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 705 a.a.
• Molecular weight: 78413.81 Da
• Isoelectric Point: 4.6408

>NTDB_id=706207 PCM89_RS13230 WP_001063343.1 2644867..2646984(+) (clpE) [Staphylococcus aureus strain C308]
MNNNFFNSDFDSILRRMMQDMQSSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQGQQGGN
GNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEI
ISIDISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATT
QDEYRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLD
ITAAHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTG
IPVSQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGN
KDALIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDSNLTDGQG
NVINFKNTIIICTSNAGFGNGTDQEYDDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGIT
MNVSQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2118 bp

>NTDB_id=706207 PCM89_RS13230 WP_001063343.1 2644867..2646984(+) (clpE) [Staphylococcus aureus strain C308]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAGCTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAGGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAGGTCAACAAGGTGGCAAT
GGCAATTATTTAGAACAAATTGGTCGCAATCTTACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGA
TAAAGAAATCCAAGAGACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGGGTTG
GTAAAACTGCGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATT
ATATCTATAGATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGA
AGGCGTTAAATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCAACTGGAAGTG
ATTCCGGTAGTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACT
CAAGATGAATATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAG
TGCTAAAGATACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACG
TATTAAAAGCATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGAT
ATTACAGCAGCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACA
TGATAAGCGTAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATA
AATTAGAAAATAGTAATGGTGAACATACTGCCGTTGCTACTGTTCATGATATTTCAGATACTATTCAACGATTAACTGGT
ATTCCAGTTTCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGG
TCAAGATCAAGCTGTAGAAATGGTTTCTCGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTG
GCAGTTTCCTATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAAT
AAAGATGCACTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGG
TTATGTCGGTTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATATTCAGTCATTCTATTTGATG
AAATCGAAAAAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATAGTAATTTGACTGATGGTCAAGGT
AATGTCATCAACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGTAACGGTACAGACCAAGAATACGA
TGACATTATGCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGTATCGTTGAATTCTTACATT
TAGATAAAGATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTCCAAGTAACATTAGATAAAAAAGGTATTACG
ATGAATGTCTCTCAAGATGCAAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACG
TATTGTTGAACAGCAAGTACGTGACAAAATTACAGATTACTATTTAGATCATACTGACGTTAAACATGTGGATTTAGATA
TCGAGGACAATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (267-366)

• ATPase family associated with various cellular activities (AAA) (AAA) (126-260)

• AAA domain (Cdc48 subfamily) (AAA_2) (451-606)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (614-685)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.131	91.064	0.438
clpC	Lactococcus lactis subsp. cremoris KW2	44.781	93.759	0.42
clpE	Streptococcus pneumoniae Rx1	47.65	87.518	0.417
clpE	Streptococcus pneumoniae TIGR4	47.65	87.518	0.417
clpE	Streptococcus pneumoniae R6	47.65	87.518	0.417
clpE	Streptococcus pneumoniae D39	47.65	87.518	0.417
clpC	Bacillus subtilis subsp. subtilis str. 168	43.798	92.624	0.406
clpC	Streptococcus thermophilus LMD-9	44.32	88.652	0.393
clpC	Streptococcus thermophilus LMG 18311	44.16	88.652	0.391
clpC	Streptococcus pneumoniae TIGR4	43.78	87.801	0.384
clpC	Streptococcus pneumoniae Rx1	43.78	87.801	0.384
clpC	Streptococcus pneumoniae D39	43.78	87.801	0.384
clpC	Streptococcus mutans UA159	43.415	87.234	0.379
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.986	92.057	0.377