Detailed information NTG0070605

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: FGCSD_RS10005
• Genome accession: NZ_AP018726
• Coordinates: 2019976..2022420 (+)
• Length: 814 a.a.
• NCBI ID: WP_129556297.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain Kdys0611
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2014976..2027420

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGCSD_RS09980 (FGCSD_1944)	-	2015101..2016384 (-)	1284	WP_129556295.1	sensor histidine kinase	-
FGCSD_RS09985 (FGCSD_1945)	-	2016385..2017728 (-)	1344	WP_129556296.1	GHKL domain-containing protein	-
FGCSD_RS09990 (FGCSD_1946)	-	2017881..2018903 (+)	1023	WP_129555386.1	IS30 family transposase	-
FGCSD_RS09995 (FGCSD_1947)	-	2019118..2019321 (+)	204	WP_003053018.1	cold-shock protein	-
FGCSD_RS10000 (FGCSD_1948)	-	2019515..2019976 (+)	462	WP_003054759.1	CtsR family transcriptional regulator	-
FGCSD_RS10005 (FGCSD_1949)	clpC	2019976..2022420 (+)	2445	WP_129556297.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FGCSD_RS10010 (FGCSD_1950)	groES	2022598..2022888 (+)	291	WP_003054738.1	co-chaperone GroES	-
FGCSD_RS10015 (FGCSD_1951)	groL	2022924..2024549 (+)	1626	WP_129556298.1	chaperonin GroEL	-
FGCSD_RS10020 (FGCSD_1952)	-	2024764..2025231 (-)	468	WP_129556299.1	8-oxo-dGTP diphosphatase	-
FGCSD_RS10025 (FGCSD_1953)	-	2025564..2027060 (-)	1497	WP_129556300.1	C69 family dipeptidase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90264.83 Da
• Isoelectric Point: 6.4813

>NTDB_id=70605 FGCSD_RS10005 WP_129556297.1 2019976..2022420(+) (clpC) [Streptococcus dysgalactiae strain Kdys0611]
MIMYSLKMQEIFRQAQFQAARFDSQYLETWHILLAMARVDHSLAGLVLSEFDAKVAVEEYEAAAILAMGKSPKDQVSHID
FRPQSKTLTNLLQFAQAISQVTKDQEVGSEHVLFAILLNPDIMATRLLEMAGYTIKDKGNGEPRLADLRKAIEIHAGYSK
EIIKAIHELRKPKKTKNQGSFSDMMKPPSTAGDLADFTRDLTEMASQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNVEDAYQILLGLKGSYETYHNVTIAD
QAVRTAVKMAHRYLTSKNLPDSAIDLLDEASATVQGMVKKSSPEIITPLDQALIDGDMKKASRLLAKDVKGQHRKPTAVT
EEDILTTLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGISHDHQAMEKRILEELKKAYRPEFINRIDEKVVFH
SLTQDNMREVVKIMVQPLMATLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGELASGHTL
KIGLSHGKLSFNIE

Nucleotide

• Length: 2445 bp

>NTDB_id=70605 FGCSD_RS10005 WP_129556297.1 2019976..2022420(+) (clpC) [Streptococcus dysgalactiae strain Kdys0611]
ATGATCATGTATTCATTGAAGATGCAAGAAATTTTCAGGCAAGCGCAGTTTCAAGCAGCCCGCTTTGATAGTCAATACCT
AGAAACTTGGCATATATTGCTAGCTATGGCGAGGGTTGATCACTCCCTAGCGGGCTTGGTGCTAAGCGAATTTGATGCTA
AGGTTGCAGTGGAAGAATATGAGGCTGCAGCTATTTTAGCGATGGGCAAAAGCCCTAAAGACCAAGTGTCTCACATTGAC
TTTAGGCCTCAGTCAAAGACCTTAACGAACCTTTTGCAATTTGCCCAAGCTATCAGTCAAGTCACCAAAGACCAAGAGGT
AGGTTCAGAGCATGTTCTCTTTGCCATTTTGCTTAATCCAGATATTATGGCGACTCGCTTATTAGAGATGGCTGGTTATA
CTATCAAGGATAAAGGAAACGGGGAGCCTCGCTTAGCTGATTTACGAAAAGCTATCGAGATTCATGCAGGCTATAGCAAG
GAAATAATTAAGGCTATCCACGAGTTGCGTAAGCCAAAGAAAACCAAAAATCAAGGTTCTTTTTCAGACATGATGAAGCC
ACCAAGCACGGCTGGGGACTTGGCGGACTTTACACGTGATTTGACCGAGATGGCAAGCCAAGGTCTCTTAGAGCCAGTTA
TTGGGCGTGATGCTGAAGTGTCACGGATGATTCAAGTACTGAGTCGTAAAACCAAGAATAACCCTGTTCTTGTGGGTGAT
GCAGGTGTGGGTAAAACGGCCCTTGCCTACGGCCTTGCTCAACGTATTGCTAATGGTGCTATTCCTTACGAACTGCAAGA
CATGCGTGTTCTAGAGTTAGACATGATGAGTGTTGTTGCGGGAACCCGTTTTCGTGGGGACTTTGAAGAGCGCATGAATC
AAATCATTGACGATATTGAGTCAGATGGCAAGATTATTCTCTTCGTAGATGAATTGCACACCATTATGGGATCAGGAAGT
GGTATTGATAGCACGCTTGATGCTGCCAATATTTTAAAACCAGCCTTATCTCGTGGAACTCTCCATATGGTGGGTGCAAC
AACGCAGGAAGAATACCAAAAACATATTGAAAAAGATGCCGCTCTTTCGCGCCGCTTTGCTAAGATTTTAATTGAAGAAC
CTAATGTAGAAGATGCTTATCAGATTCTGCTAGGACTAAAAGGCTCTTACGAGACTTACCATAATGTGACCATTGCTGAT
CAGGCTGTTAGAACCGCTGTGAAAATGGCACATCGCTATCTGACCAGCAAAAACCTTCCGGATTCTGCCATTGATTTGTT
GGATGAAGCCAGTGCTACAGTGCAAGGTATGGTTAAAAAATCTAGTCCAGAAATCATCACGCCATTAGATCAAGCTTTGA
TTGATGGCGATATGAAGAAAGCCTCTCGTTTGTTGGCAAAAGACGTTAAAGGGCAACATCGCAAGCCAACAGCTGTGACA
GAAGAGGATATCCTGACGACCTTGAGCAAGCTATCAGGTATTCCACTGGAAAAACTCAGCCAAGCTGATAGCAAAAAATA
CCTTAATTTGGAAAAAGAACTGCATAAGCGCGTGATTGGGCAAGAAGATGCTGTCTCAGCTATTTCTAGAGCCATTCGCC
GTAATCAGTCAGGCATTCGTACAGGTAAACGTCCAATCGGTTCTTTCATGTTCCTTGGTCCAACAGGGGTTGGTAAGACC
GAGTTGGCAAAAGCTTTGGCAGAAGTTCTCTTTGATGACGCGTCCGCCCTTATCCGCTTTGATATGTCAGAGTATATGGA
AAAATTTGCGGCTTCTCGCCTTAATGGCGCACCTCCAGGCTATGTCGGTTACGATGAAGGTGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTATTCTGTGCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAACGTCCTCTTACAA
GTGCTTGATGATGGCATGTTGACAGATAGCCGTGGGCGTAAAGTGGACTTCTCAAACACCATTATTATCATGACAAGTAA
TCTAGGGGCAACAGCTCTGCGTGATGATAAAACAGTTGGCTTTGGGGCAAAAGGTATCAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAGAAAGCTTACCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAC
AGCCTCACTCAGGACAATATGAGAGAAGTGGTCAAGATTATGGTGCAACCGTTGATGGCTACTTTGGCAGAAAAAGGCAT
TACCCTCAAATTCCAGCCAATGGCCCTCAAGTATTTATCAGAAGAAGGGTATGATGTGGAAATGGGTGCTCGTCCATTGC
GCCGCACTTTGCAAACTCAGGTGGAAGATAAATTGTCTGAATTGATTCTTGCTGGTGAATTGGCAAGTGGTCATACCCTG
AAAATTGGCCTTTCTCATGGAAAACTCAGCTTTAACATTGAGTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-137)

• AAA lid domain (AAA_lid_9) (376-462)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.753	99.877	0.767
clpC	Streptococcus thermophilus LMG 18311	73.039	100	0.732
clpC	Streptococcus thermophilus LMD-9	73.039	100	0.732
clpC	Streptococcus pneumoniae TIGR4	67.282	99.877	0.672
clpC	Streptococcus pneumoniae Rx1	67.282	99.877	0.672
clpC	Streptococcus pneumoniae D39	67.282	99.877	0.672
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.801	100	0.5
clpC	Bacillus subtilis subsp. subtilis str. 168	42.96	100	0.439