Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | NLY78_RS09020 | Genome accession | NZ_CP100435 |
| Coordinates | 1838627..1841080 (-) | Length | 817 a.a. |
| NCBI ID | WP_012027858.1 | Uniprot ID | A0A2K1SY42 |
| Organism | Streptococcus suis strain DE609B | ||
| Function | degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1834729..1877956 | 1838627..1841080 | within | 0 |
Gene organization within MGE regions
Location: 1834729..1877956
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NLY78_RS09000 (NLY78_08995) | dusB | 1834729..1835733 (+) | 1005 | WP_012775355.1 | tRNA dihydrouridine synthase DusB | - |
| NLY78_RS09005 (NLY78_09000) | - | 1835879..1836652 (-) | 774 | WP_012027854.1 | NUDIX domain-containing protein | - |
| NLY78_RS09010 (NLY78_09005) | pnuC | 1836645..1837466 (-) | 822 | WP_012027855.1 | nicotinamide riboside transporter PnuC | - |
| NLY78_RS09015 (NLY78_09010) | - | 1837476..1838513 (-) | 1038 | WP_012028524.1 | AAA family ATPase | - |
| NLY78_RS09020 (NLY78_09015) | clpC | 1838627..1841080 (-) | 2454 | WP_012027858.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| NLY78_RS09025 (NLY78_09020) | - | 1841086..1841544 (-) | 459 | WP_012027859.1 | CtsR family transcriptional regulator | - |
| NLY78_RS09030 (NLY78_09025) | - | 1841694..1842032 (+) | 339 | WP_012027860.1 | thioredoxin domain-containing protein | - |
| NLY78_RS09035 (NLY78_09030) | - | 1842032..1842733 (+) | 702 | WP_012027861.1 | hypothetical protein | - |
| NLY78_RS09040 (NLY78_09035) | tsf | 1842996..1844036 (-) | 1041 | WP_012027862.1 | translation elongation factor Ts | - |
| NLY78_RS09045 (NLY78_09040) | rpsB | 1844192..1844968 (-) | 777 | WP_012775356.1 | 30S ribosomal protein S2 | - |
| NLY78_RS09050 (NLY78_09045) | - | 1845315..1845827 (-) | 513 | WP_012775452.1 | adenylate kinase | - |
| NLY78_RS09060 (NLY78_09055) | - | 1846481..1851559 (-) | 5079 | WP_012775357.1 | S8 family serine peptidase | - |
| NLY78_RS09065 (NLY78_09060) | nusG | 1851703..1852242 (-) | 540 | WP_002940254.1 | transcription termination/antitermination protein NusG | - |
| NLY78_RS09070 (NLY78_09065) | secE | 1852352..1852528 (-) | 177 | WP_002940255.1 | preprotein translocase subunit SecE | - |
| NLY78_RS09075 (NLY78_09070) | rpmG | 1852538..1852690 (-) | 153 | WP_002940258.1 | 50S ribosomal protein L33 | - |
| NLY78_RS09080 (NLY78_09075) | pbp2a | 1852724..1854937 (-) | 2214 | WP_012027868.1 | penicillin-binding protein PBP2A | - |
| NLY78_RS09085 (NLY78_09080) | - | 1855090..1856058 (+) | 969 | WP_012027869.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| NLY78_RS09090 (NLY78_09085) | - | 1856060..1856926 (+) | 867 | WP_012027870.1 | RluA family pseudouridine synthase | - |
| NLY78_RS09095 (NLY78_09090) | purR | 1856953..1857765 (-) | 813 | WP_002938438.1 | pur operon repressor | - |
| NLY78_RS09100 (NLY78_09095) | - | 1857867..1858733 (-) | 867 | WP_256788106.1 | aminoglycoside phosphotransferase family protein | - |
| NLY78_RS09105 (NLY78_09100) | - | 1858733..1859674 (-) | 942 | WP_012775359.1 | 3'-5' exoribonuclease YhaM family protein | - |
| NLY78_RS09110 (NLY78_09105) | - | 1859664..1860902 (-) | 1239 | WP_012027874.1 | DNA recombination protein RmuC | - |
| NLY78_RS09115 (NLY78_09110) | - | 1860903..1861535 (-) | 633 | WP_012027875.1 | thiamine diphosphokinase | - |
| NLY78_RS09120 (NLY78_09115) | rpe | 1861528..1862187 (-) | 660 | WP_012027876.1 | ribulose-phosphate 3-epimerase | - |
| NLY78_RS09125 (NLY78_09120) | rsgA | 1862202..1863077 (-) | 876 | WP_012027877.1 | ribosome small subunit-dependent GTPase A | - |
| NLY78_RS09135 (NLY78_09130) | - | 1863974..1865551 (-) | 1578 | WP_012027878.1 | ABC transporter ATP-binding protein | - |
| NLY78_RS09140 (NLY78_09135) | - | 1865548..1866789 (-) | 1242 | WP_014636518.1 | radical SAM protein | - |
| NLY78_RS09145 (NLY78_09140) | - | 1867158..1868021 (-) | 864 | WP_012027880.1 | helix-turn-helix domain-containing protein | - |
| NLY78_RS09150 (NLY78_09145) | - | 1868511..1870955 (-) | 2445 | WP_012027881.1 | LTA synthase family protein | - |
| NLY78_RS09155 (NLY78_09150) | - | 1870968..1872698 (-) | 1731 | WP_012775361.1 | membrane protein | - |
| NLY78_RS09160 (NLY78_09155) | rsmA | 1873063..1873935 (-) | 873 | WP_012775362.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
| NLY78_RS09165 (NLY78_09160) | - | 1873955..1874485 (-) | 531 | WP_009910909.1 | DUF1697 domain-containing protein | - |
| NLY78_RS09170 (NLY78_09165) | - | 1874499..1874756 (-) | 258 | WP_012775363.1 | Txe/YoeB family addiction module toxin | - |
| NLY78_RS09175 (NLY78_09170) | - | 1874758..1875018 (-) | 261 | WP_002939010.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| NLY78_RS09180 (NLY78_09175) | - | 1875094..1875549 (-) | 456 | WP_012028534.1 | 8-oxo-dGTP diphosphatase | - |
| NLY78_RS09185 (NLY78_09180) | - | 1875556..1875885 (-) | 330 | WP_012775364.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NLY78_RS09190 (NLY78_09185) | - | 1875875..1876162 (-) | 288 | WP_012028535.1 | hypothetical protein | - |
| NLY78_RS09195 (NLY78_09190) | - | 1876260..1876628 (-) | 369 | WP_012775453.1 | hypothetical protein | - |
| NLY78_RS09200 (NLY78_09195) | rnmV | 1876621..1877190 (-) | 570 | WP_012775366.1 | ribonuclease M5 | - |
| NLY78_RS09205 (NLY78_09200) | - | 1877174..1877956 (-) | 783 | WP_012028536.1 | TatD family hydrolase | - |
Sequence
Protein
Download Length: 817 a.a. Molecular weight: 90132.53 Da Isoelectric Point: 6.3138
>NTDB_id=705387 NLY78_RS09020 WP_012027858.1 1838627..1841080(-) (clpC) [Streptococcus suis strain DE609B]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
Nucleotide
Download Length: 2454 bp
>NTDB_id=705387 NLY78_RS09020 WP_012027858.1 1838627..1841080(-) (clpC) [Streptococcus suis strain DE609B]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Streptococcus pneumoniae TIGR4 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus pneumoniae Rx1 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus pneumoniae D39 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus mutans UA159 |
66.173 |
99.143 |
0.656 |
| clpC | Streptococcus thermophilus LMG 18311 |
64.828 |
99.878 |
0.647 |
| clpC | Streptococcus thermophilus LMD-9 |
64.706 |
99.878 |
0.646 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
48.086 |
100 |
0.492 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
44.403 |
99.51 |
0.442 |