Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   NLY77_RS09920 Genome accession   NZ_CP100431
Coordinates   1975600..1976892 (-) Length   430 a.a.
NCBI ID   WP_024394375.1    Uniprot ID   -
Organism   Streptococcus suis strain 1521251     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1970600..1981892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY77_RS09910 (NLY77_09910) raiA 1974323..1974865 (-) 543 WP_004194117.1 ribosome-associated translation inhibitor RaiA -
  NLY77_RS09915 (NLY77_09915) comFC/cflB 1974942..1975607 (-) 666 WP_043032914.1 ComF family protein Machinery gene
  NLY77_RS09920 (NLY77_09920) comFA/cflA 1975600..1976892 (-) 1293 WP_024394375.1 DEAD/DEAH box helicase Machinery gene
  NLY77_RS09925 (NLY77_09925) - 1976949..1977581 (+) 633 WP_024394374.1 YigZ family protein -
  NLY77_RS09930 (NLY77_09930) cysK 1977671..1978597 (+) 927 WP_029178437.1 cysteine synthase A -
  NLY77_RS09935 (NLY77_09935) - 1978623..1978994 (-) 372 WP_024394815.1 S1 RNA-binding domain-containing protein -
  NLY77_RS09940 (NLY77_09940) - 1978996..1980396 (-) 1401 WP_172008900.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  NLY77_RS09945 (NLY77_09945) - 1980446..1981087 (-) 642 WP_024394813.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48925.50 Da        Isoelectric Point: 9.5749

>NTDB_id=705278 NLY77_RS09920 WP_024394375.1 1975600..1976892(-) (comFA/cflA) [Streptococcus suis strain 1521251]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVKNNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHSNPLVVPQKVWFSKFDDTLKKNRLVTKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPRVDVFVVQANHSLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=705278 NLY77_RS09920 WP_024394375.1 1975600..1976892(-) (comFA/cflA) [Streptococcus suis strain 1521251]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GAAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGCAAATTAAGTCGTCTTAGTTTGCCAAGGCGCTTTCATAGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTCACAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACGACTATTCTTGAACGTGGGGTGACCTTCCCACGTGTAGATGTCTTTGTTGTTCAAG
CCAATCATTCCCTCTACACAGCGTCCAGTCTTGTTCAGATTGCAGGTCGGGTTGGTAGGAGTATGGAACGTCCGACTGGT
TTACTTCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(287-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae Rx1

65.893

100

0.66
  comFA/cflA Streptococcus pneumoniae D39

65.893

100

0.66
  comFA/cflA Streptococcus pneumoniae R6

65.893

100

0.66
  comFA/cflA Streptococcus pneumoniae TIGR4

65.893

100

0.66
  comFA/cflA Streptococcus mitis SK321

65.429

100

0.656
  comFA Lactococcus lactis subsp. cremoris KW2

53.904

92.326

0.498
  comFA Latilactobacillus sakei subsp. sakei 23K

37.819

100

0.379
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

96.512

0.363